Postdoctoral Research Associate - Surgery

St Jude Children's Research Hospital; Memphis (TN); On-site; USD 50,000 - 70,000; Full time

Job summary

St Jude Children's Research Hospital is looking for a highly motivated Postdoctoral Fellow to join the Yang Lab in the Department of Surgery. This role involves conducting translational research on fusion transcriptional factors in rhabdomyosarcoma, utilizing advanced genetic and pharmacologic tools.

The ideal candidate will have a Ph.D. in relevant fields and a strong publication record. Responsibilities include experiment design, collaboration with cancer biologists, and sharing findings at meetings.

Qualifications

• Ph.D. or nearing completion in relevant fields.
• Experience with mouse models preferred.
• Strong publication record demonstrating scientific rigor.

Responsibilities

• Design experiments on chimeric transcriptional factors.
• Evaluate efficacy of immunomodulators.
• Collaborate with a multidisciplinary team.
• Present findings and contribute to manuscripts.

Skills

Excellent communication skills

Critical thinking

Collaborative mindset

Education

Ph.D. in molecular biology, cancer biology, biochemistry, developmental biology, immunology, or related fields

Tools

Mouse models

Genome editing

Job description

The Yang Lab in Department of Surgery at St. Jude Children's Research Hospital is seeking a highly motivated Postdoctoral Fellow to join our translational research team.

The research focuses on understanding the novel functions of fusion transcriptional factors in rhabdomyosarcoma. This work is highly mechanistic and translational, leveraging cutting‑edge genetic, epigenetic, cellular and pharmacologic tools to inform better therapies using human and genetic models.

Key Responsibilities

• Design and conduct experiments investigating the mechanism of chimeric transcriptional factors in regulating gene transcription.
• Evaluate preclinical efficacy of immunomodulators and the underlying mechanism.
• Collaborate within a multidisciplinary team including cancer biologists and clinicians.
• Present findings at national and international meetings and contribute to manuscript preparation and grant proposals.

Qualifications

• A Ph.D. (or nearing completion) in molecular biology, cancer biology, biochemistry, developmental biology, immunology, or related fields.
• Experience with mouse models, genome editing is a plus.
• Excellent communication skills, critical thinking, and a collaborative mindset.
• A strong publication record demonstrating scientific rigor and productivity.

St. Jude is an Equal Opportunity Employer.