Postdoctoral Research Associate (I-IV), Orthopedic Surgery

University of Arizona; Tucson (AZ); Vor Ort; USD 55.000 - 75.000; Vollzeit

Benefits dieser Stelle

Full benefits

Tuition reduction for employee and 1

Zusammenfassung

University of Arizona’s College of Medicine, Department of Orthopaedic Surgery in Tucson seeks a Postdoctoral Research Associate to advance translational and regenerative medicine projects addressing musculoskeletal trauma. The role involves in vivo and in vitro models, molecular analyses, and collaboration across teams.

The candidate will work on testing repurposed FDA‑approved drugs, contribute to publications, and support grant applications while maintaining rigorous scientific standards in a

Qualifikationen

• Advanced degree (PhD or MD) in applied pharmacology, physiology, biochemistry, translational science, or related fields.
• Documented publication history in peer‑reviewed journals.

Aufgaben

• Perform research with mice including functional testing, dosing, blood collection, tissue harvesting, and sample processing.
• Conduct immunohistochemistry, histological staining, and imaging.
• Perform molecular analyses using RT‑PCR, Western blot, ELISA, and related assays.
• Carry out in‑vitro and ex‑vivo cell culture experiments including isolation and characterization.
• Conduct scratch assays, proliferation, differentiation, migration, and co‑culture experiments.
• Analyze gene and protein targets using immunofluorescence, microscopy, flow cytometry, RT‑PCR, and Western blotting.
• Investigate therapeutic effects of FDA‑approved compounds for musculoskeletal trauma regeneration.
• Assist in or perform surgical procedures related to skin trauma in a research setting.
• Genotype and breed animals to support in vivo and in vitro knockout studies.
• Perform statistical analysis (GraphPad Prism) and present findings at conferences.

Kenntnisse

Pharmacology

Physiology

Biochemistry

Translational science

Animal models

Cell culture

Experimental design

Scientific communication

Confidentiality

Ausbildung

PhD or MD in related fields

Jobbeschreibung

Postdoctoral Research Associate (I-IV), Orthopedic Surgery

College of Medicine, University of Arizona – Department of Orthopaedic Surgery – Tucson Campus, 1501 N. Campbell Ave., Tucson, AZ 85719 USA

Department Website: https://ortho.arizona.edu/

Position Highlights

The Department of Orthopaedic Surgery at the College of Medicine, University of Arizona, in Tucson, AZ, is seeking a qualified candidate for the position of Postdoctoral Research Associate. Musculoskeletal trauma healing presents a significant and complex medical challenge, whether the injuries are isolated lesions or part of larger traumatic incidents. One major challenge in healing injuries to the skin, peripheral nerves, skeletal muscles, and bones is ensuring effective communication among cellular processes for complete regeneration and functional recovery. Our laboratory is dedicated to understanding the cellular mechanisms behind these conditions and testing repurposed FDA-approved drugs to advance outcomes from pre-clinical to clinical trials using animal and cell culture models. We are looking for a candidate committed to supporting our ongoing translational and regenerative medicine projects.

• Visa sponsorship is available for this position.

Outstanding U of A benefits include health, dental, and vision insurance plans; life insurance and disability programs; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; state retirement plan; access to UA recreation and cultural activities; and more!

Duties & Responsibilities

• Perform research activities with mice, including functional testing, dosing, blood collection, tissue harvesting, and sample processing.
• Conduct microtome/ cryotome sectioning, immunohistochemistry, and histological staining and imaging.
• Conduct molecular analyses using harvested tissue samples by RT-PCR, Western blotting, ELISA, and related laboratory assays.
• Conduct in‑vitro and ex‑vivo cell culture experiments, including cell isolation, culturing, and characterization.
• Perform scratch assays, cell proliferation, differentiation, migration, co‑culture and other experiments.
• Carry out quantitative analysis of gene and protein targets using techniques such as immunofluorescence, microscopy, flow cytometry, RT-PCR, and Western blotting.
• Apply knowledge and be involved in investigating the therapeutic effects of FDA‑approved compounds for musculoskeletal trauma regeneration.
• Assist in or perform surgical procedures related to skin trauma, such as full‑thickness excision, burns, UV injuries, and models of bone/nbone fracture and muscle denervation due to traumatic injuries, in a research setting.
• Perform animal genotyping and breeding to support in vivo and in vitro knockout studies.
• Conduct statistical analysis using GraphPad Prism.
• Demonstrate strong written and verbal communication skills to present research findings at conferences, support grant applications, and contribute to publications in peer‑reviewed journals.
• Effectively manage multiple priorities, demonstrate strong time‑management skills, and interact professionally and collaboratively with staff at all levels in a diverse, multicultural work environment.

Knowledge, Skills & Abilities

• Knowledge of pharmacology, physiology, biochemistry, translational science, or a related field.
• Ability to develop creative research hypotheses and experimental plans.
• Ability to develop research hypotheses and experimental plans.
• Skillful in animal and cell culture studies.
• Ability to communicate effectively with different groups/individuals.
• Ability to maintain confidentiality and appropriately handle sensitive information.

Minimum Qualifications

• Candidates for this position should have an advanced degree (either Ph.D., or MD) in applied pharmacology, physiology, biochemistry, translational science, or related fields.
• A documented publication history

FLSA: Exempt

Full Time/Part Time: Full Time

Number of Hours Worked per Week: 40

Job FTE: 1.0

Work Calendar: Fiscal

Job Category: Research

Benefits Eligible: Yes - Full Benefits

Rate of Pay: NIH salary guidelines, Depends on Experience

Compensation Type: salary at 1.0 full-time equivalency (FTE)

Type of criminal background check required: Name-based criminal background check (non-security sensitive)

Number of Vacancies: 1

Contact Information for Candidates

Prem Kumar Govindappa

[e-mail]

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