Postdoctoral Research Associate - Gottschalk lab

Thecentermemphis; Memphis (TN); On-site; USD 52,000 - 68,000; Full time

Job summary

St. Jude Children's Research Hospital is offering a fully supported Postdoctoral Research Associate position to develop T-cell–based therapies for pediatric solid and brain tumors. The project emphasizes genetic engineering to enhance specificity and effector function in preclinical models.

You will join a collaborative group focused on translating these immune strategies toward early-phase clinical testing, with strong support for professional development and a human-centered hiring approach.

Qualifications

• Ph.D. required with strong publication record in immunology or related field.
• Experience in generating and evaluating human or murine immune cells and gene editing is preferred.

Responsibilities

• Develop and optimize immune-based therapies using genetic engineering in preclinical models.
• Translate approaches into early phase clinical testing in collaboration with the lab team.

Skills

Immunology

Cell biology

Genetics

Genomics

T-cell biology

Education

Ph.D. in molecular biology / cell biology / genetics / genomics / immunology or related field

Tools

Flow cytometry

Single-cell transcriptomics

Job description

A postdoctoral research associate position is available with Dr. Gottschalk.

The Gottschalk Laboratory is seeking a highly motivated and creative candidate for a fully supported postdoctoral fellowship to develop immune-based therapies. The postdoctoral fellow will join a collaborative research group that strives to build and maintain a culture of respect and collaboration. Likewise, the Gottschalk Laboratory cares deeply about the success and professional growth of its lab members. The research project is aimed to develop T-cell-based therapies for pediatric solid and brain tumors. Studies are focused on using genetic engineering approaches to not only render immune cells cancer specific, but also improve their effector function. Genetically modified immune cells will be studied in preclinical models with special emphasis on how adoptively transferred cells interact with tumor cells, the tumor microenvironment, and resident immune cells. Ultimate goal of these studies is to translate these approaches into early Phase clinical testing.

Minimum Education Requirements

Successful applicants will have a strong publication record, excellent communication skills, and a Ph.D. or equivalent degree in molecular biology, cell biology, genetics, genomics, immunology, or a related area. To succeed in this position, you will have a strong immunology and cell biology background, with an emphasis on cellular immunology, and genetic manipulation of mammalian cells. Applicants with experience in generating and evaluating human or murine immune cells, gene editing, single cell transcriptomics, flow cytometry, and murine solid tumor models are strongly encouraged to apply.

We are committed to a human-centered hiring experience. Technology may support portions of our process, but recruiting decisions involve human review and engagement. Learn more about our approach to AI.

St. Jude is an Equal Opportunity Employer

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