Postdoc - T-Cell Immunotherapy for Pediatric Cancer

St. Jude; Memphis (TN); On-site; USD 52,000 - 70,000; Full time

Job summary

St. Jude Children’s Research Hospital in Memphis, TN, invites applications for a postdoctoral research associate in the Gottschalk Laboratory to develop T-cell–based therapies for pediatric solid and brain tumors.

The fellowship supports a collaborative team focused on genetic engineering to render immune cells tumor-specific and to enhance their effector function, while studying interactions with tumor cells, the tumor microenvironment, and resident immune cells.

Qualifications

• Ph.D. or equivalent in molecular biology, cell biology, genetics, genomics, immunology, or related field.
• Strong immunology and cell biology background with emphasis on cellular immunology and genetic manipulation of mammalian cells.
• Applicants with experience in generating and evaluating human or mouse immune cells, gene editing, single cell transcriptomics, flow cytometry, and murine solid tumor models are encouraged to apply.

Responsibilities

• Develop T-cell-based therapies for pediatric solid and brain tumors.
• Engineer immune cells to be cancer-specific and enhance their effector function.
• Study interactions with tumor cells, tumor microenvironment, and resident immune cells.
• Translate findings toward early-phase clinical testing.

Skills

Publication record

Excellent communication skills

Immunology background

Genetic manipulation

Preclinical models experience

Education

Ph.D. or equivalent in molecular biology, cell biology, genetics, genomics, immunology, or related field

Tools

Flow cytometry

Gene editing techniques

Single-cell transcriptomics

Job description

St. Jude Children’s Research Hospital in Memphis, TN, invites applications for a postdoctoral research associate in the Gottschalk Laboratory to develop T-cell–based therapies for pediatric solid and brain tumors.

The fellowship supports a collaborative team focused on genetic engineering to render immune cells tumor-specific and to enhance their effector function, while studying interactions with tumor cells, the tumor microenvironment, and resident immune cells.