Postdoctoral Research Associate, Department of Basic Medical Sciences (College of Medicine-Phoenix)

University of Arizona; Phoenix (AZ); On-site; USD 60,000 - 75,000; Full time

Job summary

The University of Arizona College of Medicine – Phoenix seeks a Postdoctoral Research Associate to join the Lab of Dr. Halmai in basic medical sciences.

You will establish and characterize patient-derived 3D organoid cultures from tumor biopsies to define cancer subtypes, targets, and biomarkers for precision medicine. The role requires a PhD in a biomedical field and experience in molecular biology or genomics.

Qualifications

• PhD in a biomedical field is required.
• Experience in molecular biology, genomics, or primary cell culture.
• Strong communication and teamwork.
• Ability to design and execute research plans.

Responsibilities

• Establish and maintain cancer 3D organoid lines.
• Perform molecular and cellular assays.
• Conduct CRISPR/Cas9 edits and screens to characterize genomic alterations.
• Perform inhibitor screens to identify therapeutic vulnerabilities.
• Conduct cancer genomics research under the PI.
• Develop and conduct complex research projects.
• Formulate methods and analyze data with independent judgment.
• Foster collaborations within the department and across the University.
• Present results at meetings and conferences.
• Prepare manuscripts for peer-reviewed journals.
• Participate in grant writing with preliminary data.
• Develop protocols as dictated by results.
• Assist supervision of lab staff.
• Contribute to daily lab operations.

Skills

Lab skills

Statistics

Independent research

Communication skills

Grant writing

Imaging software

Education

PhD in Genetics/Genomics

Tools

CRISPR/Cas9 genome editing

Job description

Postdoctoral Research Associate, Department of Basic Medical Sciences (College of Medicine-Phoenix)

Postdoctoral Research Associate, Department of Basic Medical Sciences (College of Medicine-Phoenix)

The Lab of Dr. Nicole Halmai in the Department of Basic Medical Sciences seeks a motivated researcher to join our functional genomics and cancer genomic medicine research team. The position involves establishing, characterizing, and manipulating 3D cell cultures (patient-derived organoid lines) from human tumor biopsies to elucidate clinically relevant molecular subtypes, drug targets, and biomarkers for improved cancer treatment and precision medicine, with the ultimate goal of addressing cancer health disparities.

Candidates should hold a Ph.D. in Genetics/Genomics, Molecular/Cellular Biology, Biomedical Sciences, Physiology, or a field broadly related to biomedical research with a research emphasis. Required qualifications include research experience in at least one of the following areas: molecular biology, genomics, or primary cell culture. Successful candidates will demonstrate strong communication skills and the ability to work both independently and collaboratively.

This position is eligible for visa sponsorship.

The University of Arizona College of Medicine – Phoenix anchors the 28-acre Phoenix Bioscience Core in the heart of the Valley of the Sun. The College inspires and trains individuals to become exemplary physicians, scientists and leaders who are life-long learners and inquisitive scholars. The Phoenix Biomedical Campus embodies the University’s priorities of engagement, partnership, innovation, and synergy in its world-class academic and research initiatives, with clinical facilities throughout Greater Phoenix.

Outstanding U of A benefits include health, dental, vision, and life insurance; paid vacation, sick leave, and holidays; U of A/ASU/NAU tuition reduction for the employee and qualified family members; access to U of A recreation and cultural activities; and more!

Duties & Responsibilities

• Establish and maintain cancer 3D organoid lines derived from patient tumor and normal biopsies.
• Perform molecular and cellular assays to characterize organoid lines.
• Perform CRISPR/Cas9 editing experiments, including CRISPR screens, to functionally characterize cancer-associated genomic alterations.
• Perform targeted inhibitor screens to detect therapeutic vulnerabilities in organoid lines.
• Conduct advanced, multi-disciplinary research in cancer genomics under the direction of the principal investigator, Dr. Halmai.
• Develop, design, and conduct complex research projects.
• Formulate research methods, develop research criteria, and perform scientific data collection and analysis using independent judgment.
• Foster collaborations within the Department and with other units across the University.
• Present results at laboratory meetings and conferences.
• Prepare manuscripts for publication in peer-reviewed journals.
• Participate in grant writing, including generating preliminary data, submitting grant applications, and preparing progress reports.
• Develop and implement protocols as dictated by experimental results.
• Assist with supervision of laboratory staff.
• Contribute to daily lab operations.

Knowledge, Skills, and Abilities (KSAs):

• Excellent laboratory and analytical skills and commitment to scientific excellence and innovation.
• Knowledge of statistics and data analysis and interpretation.
• Ability to conduct research independently and within a team.
• Ability to communicate professionally in a clear, concise manner orally and in writing.
• Knowledge of grant writing and manuscript preparation.
• Proficiency with imaging or data analysis software.

Minimum Qualifications

• PhD in Genetics/Genomics, Molecular/Cellular Biology, Biomedical Sciences, Physiology, or a related field of study required.

Preferred Qualifications

• Track record of publications in peer-reviewed journals.
• Interest in cancer genomic medicine and cancer health disparities.
• Experience in primary cell culture or functional genomics.
• CRISPR/Cas9 genome editing experience.
• Cancer genomic medicine or functional genomics research experience.

FLSA Exempt

Full Time/Part Time Full Time

Number of Hours Worked per Week 40

Job FTE 1.0

Work Calendar Fiscal

Job Category Research

Benefits Eligible Yes - Full Benefits

Rate of Pay NIH salary guidelines, Depends on Experience

Compensation Type salary at 1.0 full-time equivalency (FTE)

Type of criminal background check required: Name-based criminal background check (non-security sensitive)

Number of Vacancies 1

Contact Information for Candidates Office of Talent Acquisition
[e-mail]

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