Postdoctoral Positions in Functional Transcriptomics, Cell Signaling, and Cancer Immunotherapy

University of Pennsylvania Perelman School of Medicine; Pennsylvania; On-site; USD 52,000 - 62,000; Full time

Job summary

The Thomas-Tikhonenko laboratory at University of Pennsylvania: Perelman School of Medicine is recruiting postdoctoral fellows to pursue newly funded basic and translational research projects aimed at elucidating the role of aberrant mRNA splicing in defining cancer vulnerabilities and identifying new targets for therapy.

Our work spans hematologic malignancies and solid tumors, in a setting that promotes collaboration on a campus shared with CHOP and the Abramson Cancer Center.

Qualifications

• Strong candidates will hold PhD, MD, DVM, or equivalent doctoral degrees and have demonstrated expertise in at least one of the following fields: RNA biology, cancer genetics/genomics, cell signaling, immunotherapy, or bioinformatics.

Responsibilities

• Pursue newly funded basic and translational research projects.
• Elucidate the role of aberrant mRNA splicing in defining cancer vulnerabilities and identifying new targets for therapy.

Skills

RNA biology

Cancer genetics/genomics

Cell signaling

Immunotherapy

Bioinformatics

Education

PhD, MD, DVM or equivalent

Job description

University of Pennsylvania: Postdoctoral Positions: Perelman School of Medicine Postdoctoral

Location

University of Pennsylvania - Perelman School of Medicine

Open Date

Oct 27, 2026

Description

The Thomas-Tikhonenko laboratory is recruiting postdoctoral fellows to pursue newly funded basic and translational research projects aimed at elucidating the role of aberrant mRNA splicing in defining cancer vulnerabilities and identifying new targets for therapy. Our research spans hematologic malignancies and solid tumors, combining mechanistic studies with the development of novel immunotherapies. Please visit the lab website for ongoing projects, recent publications, and current members. We are located in the Colket Translational Research Building of Children's Hospital of Philadelphia, which shares a contiguous campus with the University of Pennsylvania's Perelman School of Medicine. This setting provides ample opportunities for interactions with the NCI-designated Abramson Cancer Center, the Institute for Immunology and Immune Health, the Institute for Biomedical Informatics, and other research programs.

Qualifications

We seek ambitious scientists who thrive on challenges, enjoy working in a highly collaborative and dynamic research environment, and are eager to make their marks. Strong candidates will hold PhD, MD, DVM, or equivalent doctoral degrees and have demonstrated expertise in at least one of the following fields: RNA biology, cancer genetics/genomics, cell signaling, immunotherapy, or bioinformatics. Recent graduates with strong research accomplishments in adjacent areas are also encouraged to apply. Eligibility for federal training grants is a plus but not a requirement.