Postdoctoral fellowship in neurogenomics

National Institutes of Health (NIH); Bethesda (MD); On-site; USD 65,000 - 90,000; Full time

Job summary

The Neurodegenerative Diseases Research Unit (NDRS) at NIH/NINDS in Bethesda, MD invites applications for a postdoctoral fellow in neurogenomics and computational biology. The position centers on large-scale genomic and multi-omic analyses to uncover disease genes and mechanisms in neurodegenerative disorders.

The fellow will lead computational analyses of sequencing and GWAS data, contribute to translational studies, and present findings at national and international meetings.

Qualifications

• MD or PhD in a life science discipline.
• Experience analyzing next-generation sequencing and/or GWAS datasets.
• Strong data visualization and programming in Linux, R, and Python.
• Excellent analytical, organizational, and problem-solving skills.
• Strong communication and presentation abilities; collaborative mindset.

Responsibilities

• Lead computational analyses of genomic and multi-omic data for gene discovery.
• Contribute to translational and functional studies design and interpretation.
• Present research findings at national and international meetings.
• Foster a collaborative team-science environment.

Skills

Genomic data analysis

GWAS analysis

Data visualization

Bioinformatics (Linux, R, Python)

Collaboration

Communication skills

Education

MD/PhD in life sciences

Tools

Linux

R

Python

Job description

The Neurodegenerative Diseases Research Unit (NDRS), part of the National Institute of Neurological Disorders and Stroke, is seeking a highly motivated postdoctoral fellow in neurogenomics and computational biology.

Laboratory description:

TheNDRS, headed by Dr. Sonja W. Scholz, is an internationally recognized neurogenetics laboratory located at the NIH campus in Bethesda, MD, USA. Our research program focuses on understanding the genetic and molecular mechanisms underlying complex neurodegenerative diseases, including Lewy body dementia, multiple system atrophy, frontotemporal dementia, and other rare diseases. As part of the NIH Intramural Research Program, the laboratory provides access to a uniquely collaborative and interdisciplinary research environment, state-of-the-art sequencing technologies, large-scale genomic and multi-omic datasets, high-performance computational resources, and extensive expertise in human genetics, bioinformatics, and translational neuroscience.

Our long-term goal is to identify the genetic and molecular factors that influence disease risk, progression, and clinical heterogeneity, and to leverage genomic and multi-omic technologies to develop novel biomarkers and precision medicine approaches for neurodegenerative disorders. Current research projects integrate genome-wide association studies (GWAS), whole-genome sequencing, transcriptomics, epigenomics, proteomics, and functional genomic analyses.

Fellowship description:

We are searching for an enthusiastic, collaborative, and intellectually curious scientist to join our team. The successful candidate will lead and contribute to innovative research projects involving large-scale genomic and multi-omic data analysis in neurodegenerative diseases.

The fellow will be expected to:

• Perform computational analyses of genomic and other omic datasets for gene discovery. Contribute to the design and interpretation of translational and functional studies. Present research findings at national and international scientific meetings. Contribute to a collaborative team science environment.

The ideal candidate will have a strong interest in the genetics and biology of neurodegenerative disease and a desire to work at the interface of genomics, bioinformatics, and translational neuroscience.

Required qualifications:

• M.D. or Ph.D. (or M.D., Ph.D.) in a relevant life science discipline

• Experience analyzing next-generation sequencing and/or GWAS datasets Experience in data visualization Knowledge and experience in bioinformatic programming using Linux, R, and Python Excellent analytical, organizational, and problem-solving skills Strong communication and presentation skills, both oral and written The ability to work effectively in a highly collaborative research environment

Interested candidates should contact Dr. Sonja Scholz (e-mail: [e-mail]). Please provide an updated CV, a cover letter describing research interests and career goals, and three references in your application.

DHHS and NIH are Equal Opportunity Employers

Selection for this position will be based solely on merit, with no discrimination for non-merit reasons such as race, color, religion, gender, sexual orientation, national origin, political affiliation, marital status, disability, age, or membership or non-membership in an employee organization. The NIH encourages the application and nomination of qualified women, minorities, and individuals with disabilities.