Postdoctoral Fellow: Ubiquitin Pathway & Structural Biology

Dana-Farber Cancer Institute (DFCI); Boston (MA); On-site; USD 72,000 - 76,000; Full time

Job summary

Dana-Farber Cancer Institute in Boston, MA invites applications for a Postdoctoral Research Fellow in the Fischer Lab. The position focuses on biochemistry and structural biology projects addressing ubiquitin signaling and protein homeostasis, leveraging cryo-EM, X-ray, NMR and mass spectrometry in a collaborative environment.

The successful candidate will join a multidisciplinary team of scientists to develop and execute complex experiments, analyze data, and contribute to publications.

Qualifications

• Recent Ph.D. or equivalent in structural biology, biochemistry, biophysics or molecular biology.
• Proven ability to develop and execute on complex structural biology projects.
• Ability to collect and analyze experimental data, prepare research publications and communicate results
• Ability to work in a collaborative and team environment
• Excellent oral and written capabilities
• Expertise in recombinant protein expression and purification
• Experience with insect and/or mammalian expression systems
• Proficiency in data collection and structure determination for either X-ray or cryo-EM
• Experience with protein biophysical techniques
• In vitro biochemistry and enzyme kinetics
• Quantitative and computational skills

Responsibilities

• Note: The HTML describes a postdoctoral research role focusing on biochemistry and structural biology projects.

Skills

Structural biology

Biochemistry

Biophysics

Molecular biology

Data analysis

Communication skills

Education

PhD in structural biology / biochemistry / biophysics / molecular biology

Tools

Cryo-EM

X-ray crystallography

NMR

timsTOF Pro

Orbitrap Eclipse

Job description

Dana-Farber Cancer Institute in Boston, MA invites applications for a Postdoctoral Research Fellow in the Fischer Lab. The position focuses on biochemistry and structural biology projects addressing ubiquitin signaling and protein homeostasis, leveraging cryo-EM, X-ray, NMR and mass spectrometry in a collaborative environment.

The successful candidate will join a multidisciplinary team of scientists to develop and execute complex experiments, analyze data, and contribute to publications.