Postdoctoral Fellow-MSH-30025-251

Mount Sinai Medical Center; New York (NY); On-site; USD 72,500 - 80,000; Full time

Benefits offered by this job

Mentorship

Access to state-of-the-art technologies

Strong support for career development

Job summary

Mount Sinai Medical Center is looking for a dedicated researcher in cancer biology to design and execute independent projects. The ideal candidate will hold a Ph.D. in a relevant field and have a strong record of research productivity. Responsibilities include conducting experiments and contributing to manuscripts and grant proposals.

The position offers a competitive salary of $72,500 to $80,000 annually, depending on experience.

Join a dynamic NIH-funded laboratory and receive mentorship, cutting-edge technology access, and support for career development.

Qualifications

• Ph.D. in Cancer Biology, Molecular Biology, Genetics, Epigenetics, or Stem Cell Biology.
• Strong publication record or evidence of research productivity.
• Experience with organoids, mouse models, or molecular biology techniques.

Responsibilities

• Design and execute independent research projects in cancer biology.
• Conduct experiments using organoid and cellular models.
• Contribute to manuscripts and grant applications.

Skills

Molecular biology

Mammalian cell culture

Research productivity

Collaboration

Education

Ph.D. in Cancer Biology or related field

Tools

Genetic barcoding

CRISPR technologies

Single-cell multiomics

Job description

Research Focus

Our research aims to uncover the molecular mechanisms that govern cancer cell behavior by focusing on functional heterogeneity within tumors, phenotypic plasticity during tumor evolution and therapy response, and cellular competence in tumor initiation, adaptation, and drug resistance.

Rather than simply cataloging cellular states, we seek to identify the mechanisms that establish, maintain, and regulate them using genetic barcoding–based lineage tracing, functional genomics, organoid and mouse models, CRISPR perturbations, and single‑cell multiomics to track cancer evolution at clonal resolution and uncover causal regulators of cancer cell identity and behavior.

Current Research Areas

• Cellular competence and tumor evolution
• Phenotypic plasticity, memory, and adaptation
• Developmental programs and cancer cell states

Responsibilities

• Design and execute independent research projects.
• Perform experiments using organoid, cell culture, and mouse models.
• Conduct genetic barcoding, lineage tracing, and functional genomics studies.
• Contribute to manuscripts, grant applications, and mentoring activities.

Qualifications

Required

• Ph.D. in Cancer Biology, Molecular Biology, Genetics, Epigenetics, Stem Cell Biology, or a related field.
• Strong publication record or evidence of research productivity.
• Ability to work independently and collaboratively.
• Experience with molecular biology and mammalian cell culture.

Preferred

• Experience with organoids or mouse models.
• Experience with genetic barcoding, clonal tracking, and lineage tracing.
• Experience with single-cell genomics and multiomics.
• Experience with ATAC‑seq, RNA‑seq, CUT‑Tag, or CUT‑RUN.
• Experience with CRISPR technologies.

Benefits

Join an NIH‑funded laboratory and help shape an ambitious research program at the intersection of cancer biology, epigenetics, stem cell biology, and genomics. Trainees receive close mentorship, access to state‑of‑the‑art technologies, and strong support for career development and scientific independence.

Equal Opportunity Employer

Mount Sinai is an equal opportunity employer. We do not discriminate based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender identity, veteran status, or any other characteristic protected by law. We are committed to fostering an inclusive environment where all faculty, staff, students, and trainees feel respected and supported.

Salary

Salary range: $72,500 – $80,000 annually, depending on experience, education, and operational need. The range does not include bonuses, differential pay, or other compensation.