Postdoctoral Fellow: GPCR-cAMP Signaling Research

Novartis; Cambridge (MA); On-site; USD 74,000 - 100,000; Full time

Benefits offered by this job

Guidance from leaders

Access to advanced technologies

Global scientific community

Job summary

Novartis invites applications for a Postdoctoral Research Fellow position in Cambridge, MA, joining the Discovery Sciences team to pursue an innovative project at the forefront of biomedical science and drug discovery. This full-time fellowship runs up to three years and emphasizes multidisciplinary collaboration and hands-on training.

The role focuses on GPCR and cAMP signaling, leveraging cellular tools, human genetics, genomics, chemical biology and pharmacology to uncover mechanisms.

Qualifications

• PhD (or equivalent) completed prior to the fellowship start date (PhD conferred in 2026 only).
• Demonstrated record of scientific achievement (publications, presentations, patents, or equivalent).
• Strong commitment to learning, innovation, fundamental exploratory research and professional development.
• Basics in cell culture, genetics, developmental biology, molecular biology and biochemistry techniques.
• Excellent analytical, communication, presentation and organizational skills.
• Boundless curiosity.

Responsibilities

• Shape your postdoc project by dedicating your efforts to multiple possible key scientific questions.
• Combine diverse available tools to consolidate your research strategy (in vitro assays, pharmacological tools, genetic studies, animal models).
• Design, implement and advance scientific experiments to uncover novel mechanisms underlying cAMP-dependent signaling.
• Unravel the interaction of GPCRs with less characterized cAMP pathway nodes and understand mode of action.
• Increase understanding of novel pharmacological target classes either by in depth characterization of single members of questioned pathways or by gaining insights in unexplored general interaction specificities.
• Work independently as well as with interdisciplinary teams and interact with diverse teams covering a broad spectrum of expertise.

Skills

Cell culture

Genetics

Developmental biology

Molecular biology

Biochemistry

Analytical skills

Communication

Presentation skills

Organizational skills

Curiosity

Education

PhD in a relevant scientific discipline

Job description

Novartis invites applications for a Postdoctoral Research Fellow position in Cambridge, MA, joining the Discovery Sciences team to pursue an innovative project at the forefront of biomedical science and drug discovery. This full-time fellowship runs up to three years and emphasizes multidisciplinary collaboration and hands-on training.

The role focuses on GPCR and cAMP signaling, leveraging cellular tools, human genetics, genomics, chemical biology and pharmacology to uncover mechanisms.