Postdoctoral Fellow, Chemistry Lewis Lab

Indiana University Bloomington; Bloomington (IN); On-site; USD 55,000 - 70,000; Full time

Job summary

Indiana University Bloomington in Bloomington, IN, invites applications for a Postdoctoral Fellow position in the Lewis Lab within the Department of Chemistry. The role focuses on developing and applying cutting-edge protein engineering techniques to address challenges in synthetic chemistry and biocatalysis.

The successful candidate will leverage organic and organometallic chemistry with state-of-the-art methods in generative protein design, directed evolution, and next-gen sequencing to

Qualifications

• PhD in chemistry or biochemistry required.
• Experience with molecular biology or synthetic chemistry is required.
• Familiarity with computational design tools and organometallic catalysis is highly desirable.

Responsibilities

• Primary research: cloning or molecular biology for enzyme production and engineering, synthesis of substrates and standards, high-throughput screening of enzyme libraries, and application of computational protein design.
• Documentation of findings, preparation of reports and presentations, and participation in group equipment/facility maintenance.

Skills

Molecular biology

Synthetic chemistry

Computational design tools

High-throughput screening

Enzyme library generation

Education

PhD in chemistry or biochemistry

Tools

Next-gen sequencing

Computational protein design

Job description

Posting Details

Position Details

Title

Postdoctoral Fellow, Chemistry Lewis Lab

Appointment Status

Non-Tenure Track

Department

IU Bloomington Chemistry

Location

Bloomington

Department Information

The Department of Chemistry in the College of Arts + Sciences atIndiana University, consists of a well-rounded research communitywith cutting-edge expertise in a wide variety of modern disciplinesincluding analytical chemistry, organic chemistry, inorganicchemistry, physical chemistry, materials chemistry, andbiochemistry. Indiana University is an equal employment andaffirmative action employer and a provider of ADA services andprohibits discrimination in hiring. See Indiana UniversityNotice of Non-Discrimination here which includes contactinformation.

Job Summary

The Lewis Lab in the Department of Chemistry at Indiana Universityis accepting applications for a Postdoctoral Fellow position. The position offers an opportunity to develop and apply cutting- edgeprotein engineering techniques to address fundamental challenges insynthetic chemistry and biocatalysis. The successful applicant willuse a deep understanding of organic and organometallic chemistry,combined with state-of-the-art methods generative protein design,directed evolution, next gen sequencing, and laboratory automationto develop B12-dependent enzymes or artificial metalloenzymescontaining different organometallic cofactors for new chemicaltransformations. Motivated applicants with PhD training in any areaof chemistry or biochemistry will be considered. Experience witheither molecular biology or synthetic chemistry is stronglypreferred.

The Lewis Lab is a dynamic multidisciplinary laboratoryenvironment. The successful applicant will play an integral rolewithin our growing team of chemists, biochemists, and proteinengineers and will emerge with a skill set that is equally relevantto academia and industry. Trainees receive regular guidance andfeedback to ensure progress is made toward their career goals,whatever those may be. Trainees are also afforded the schedulingflexibility needed to maintain an appropriate work lifebalance.

Responsibilities

Primary research responsibilities will include cloning and othermolecular biology required for enzyme production and engineering,synthesis of substrates and product standards, high throughputscreening of enzyme libraries, and application of computationalprotein design tools. Careful documentation of all findings, formalresearch reports and presentations, and participation in groupequipment/facility maintenance is also expected.

Basic Qualifications

Required Qualifications

Candidates must have extensive experience with either molecular biology or synthetic chemistry. PhD in any area of chemistry or biochemistry.

Preferred Qualifications

Experience with both molecular biology and synthetic chemistry is preferred but not required. Familiarity with computational design tools, organometallic catalysis/methodology development, enzyme library generation and screening are highly desirable.

Department Contact for Questions

The initial appointment for this position will be for 12 months. Additional 12-month extension will be available based on performance. A competitive salary along with a benefits package will be offered.

Questions regarding the position or application process can be directed to: Prof. Lewis, Department of Chemistry, Indiana University, 800 E. Kirkwood Avenue, Bloomington, IN 47405,[e-mail].

For additional information visit:

https://lewis.lab.indiana.edu/

For Best Consideration Date

07/21/2026

Expected Start Date

10/01/2026

Posting Number

IU-101599-2026