Postdoctoral Fellow - Cancer Genetics and Epigenetics

aa067; Duarte (CA); On-site; USD 52,000 - 66,000; Full time

Job summary

City of Hope, Beckman Research Institute, is seeking a highly motivated postdoctoral fellow in the Department of Cancer Genetics and Epigenetics. The successful candidate will study transcriptional regulation and RNA metabolism during development and disease, employing CRISPR genomic screens, single-cell transcriptomics, and mouse models to understand chromatin biology and RNA modification.

The position emphasizes independent research, collaboration, and rigorous data documentation, with an

Qualifications

• PhD in Biochemistry, Molecular and Cellular Biology or related field.
• Strong interest in basic and translational research.
• Meticulous record keeping and attention to detail.
• Evidence of productivity through first-author publications.
• Ability to work independently and in a team.
• Self-motivated with a proven track record of productivity.

Responsibilities

• Study transcriptional regulation and RNA metabolism in development and disease.
• Utilize biochemistry, molecular biology, CRISPR-based genomic screens, single-cell transcriptomics, and mouse models to investigate Arg methylation in chromatin biology, RNA splicing, and RNA modification.

Skills

Biochemistry

Molecular biology

CRISPR screening

Single-cell RNA-seq

Genetically modified mice

Publication track record

Independent research

Team collaboration

Education

PhD in Biochemistry, Molecular and Cellular Biology

Tools

CRISPR

Single-cell transcriptomics

Job description

Join the forefront of groundbreaking research at City of Hope where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

The laboratory of Dr. Yanzhong Yang in the Department of Cancer Genetics and Epigenetics at the Beckman Research Institute of City of Hope Cancer Center is looking for a highly motivated postdoctoral fellow.

For more information about Dr. Yang lab, please visit here.

As a successful candidate you will:

• Study transcriptional regulation and RNA metabolism in normal development and human diseases, such as neurological disorder, immunology, and cancer.
• Utilize biochemistry, molecular biology, CRISPR-based genomic screen, single-cell transcriptomics, and genetically modified mouse models to investigate the role of protein arginine methylation in the regulation of chromatin biology, RNA splicing, and RNA modification in mammalian cells.

Your qualifications should include:

• A PhD in Biochemistry, Molecular and Cellular Biology, or related area.
• Strong interest in basic and translational research.
• Strong work ethic, meticulous and detail-oriented record keeping habits.
• Evidence of productivity reflected in first author publications in peer-reviewed journals.
• Ability to conduct independent research and work effectively in a team.
• The candidate should be self-motivated, with a proven track record of productivity.

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.