Postdoctoral Fellow, Biochemistry and Microbiology Division

New England Biolabs; Ipswich (MA); On-site; USD 67,000 - 81,000; Full time

Job summary

New England Biolabs is inviting applications for a Postdoctoral Fellow to study nucleases using in vitro biochemistry and structural biology. The role focuses on characterizing mechanism, substrate specificity, and enzyme discovery via genome mining and functional screening.

The successful candidate will publish findings, present results, and collaborate across teams in a campus-like environment that values scientific rigor and integrity.

Qualifications

• Ph.D. in Biochemistry, Chemistry, Molecular Biology, or a related discipline.
• Excellent verbal and written communication skills.
• Ability to work both independently and collaboratively.

Responsibilities

• Design and execute experiments to characterize exonuclease and endonuclease biochemistry.
• Create high-throughput activity assays for enzyme discovery.
• Communicate discoveries through publications and presentations.
• Collaborate with internal and external colleagues.
• Maintain rigorous data quality and documentation practices.

Skills

Excellent communication

Independent & collaborative work

Education

Ph.D. in Biochemistry, Chemistry, Molecular Biology, or related

Tools

Genome mining

NGS-based assays

Job description

About NEB

New England Biolabs® is a different kind of biotechnology company - we are a community of scientists, innovators and collaborators driven by a shared mission to advance science for the benefit of society. Founded in 1974 with a deep commitment to research excellence and environmental stewardship, NEB® has become a global leader in the discovery and production of enzymes for molecular biology applications. Our reagents are trusted by researchers worldwide for their quality and reliability and have played a critical role in breakthroughs across genomics, proteomics, diagnostics and academic research. With a corporate culture rooted in passion, humility and authenticity, we offer a dynamic and inclusive workplace where creativity thrives, voices are heard, and personal growth is celebrated. Whether you are interested in pursuing a research career or supporting our mission through other roles, joining NEB means contributing to meaningful scientific progress in a collaborative, campus-like environment that values both innovation and integrity.

The Role

The Research Department invites applications for a Postdoctoral Fellow to engage in research on nucleases. The Postdoctoral Fellow will use in vitro biochemistry and structural biology to characterize the mechanism and substrate specificity of known nucleases and discover new enzymes via genome mining and functional screening. Successful candidates will demonstrate strong scientific communication skills and will have an interest in both basic and applied research.

How you will contribute:

• Design and execute experiments to characterize exonuclease and endonuclease biochemistry, including enzyme kinetics and NGS-based assays
• Create clever, high-throughput activity assays for enzyme discovery
• Communicate discoveries and findings to the scientific community through publications and presentations
• Collaborate with internal and external colleagues
• Maintain high standards of scientific rigor, quality of data, and documentation practices

Required Qualifications and Experience:

• Ph.D. in Biochemistry, Chemistry, Molecular Biology, or a related discipline
• Excellent verbal and written communication skills
• Publication of original scientific work in high-quality journals
• Ability to work both independently and collaboratively

What will make you stand out:

• Experience in biochemical and structural characterization of nucleic acid enzymes
• Technical expertise in enzymology, including kinetics
• Experience with enzyme superfamily studies, including genome mining, phylogenetic tree analysis, and ancestral sequence reconstruction
• Submission of a cover letter with your application is highly encouraged

Estimated base salary for a Postdoctoral Fellow is $74,000

Benefits at NEB

Base salary decisions depend on several factors, including, but not limited to, individual qualifications, job location, internal equity, and market data alignment.

Equal Opportunity Employer, including disabled/veterans

New England Biolabs is committed to fostering an inclusive community. As an Equal Employment Opportunity employer, New England Biolabs considers applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, age, qualified physical or mental disability, transgender status, marital status, ethnicity, pregnancy, childbirth, or related medical conditions, or status as a disabled veteran or any other protected veteran, in all phases of the employment process and in compliance with applicable federal, state, and local laws and regulations. More in-depth details of EEO are available here.

New England Biolabs is a participating employer in the Employment Verification ( E-Verify ) program.