Postdoctoral Fellow-Arthroplasty Research Lab

Hospital for Special Surgery; New York (NY); On-site; USD 71,564 - 78,010; Full time

Job summary

Hospital for Special Surgery in New York, NY invites a Postdoctoral Fellow to join the Arthroplasty Research Laboratory.

The role focuses on developing novel approaches for limb regeneration using autologous skeletal stem cells, and includes collaboration with NIH-funded projects and DoD projects.

Responsibilities include designing experiments, data analysis, manuscript drafting, and contributing to animal studies, histology, and imaging, with strong emphasis on rigorous scientific writing.

Qualifications

• PhD or MD required for appointment.
• Postdoctoral experience in developmental biology, cell and molecular biology, or neuroscience preferred.
• Excellent technical skills in tissue culture, histology, immunoassays, and microscopy.

Responsibilities

• Design and execute experiments in cell and molecular biology and animal models.
• Collect and analyze data; maintain detailed lab records.
• Draft manuscripts and present findings in lab meetings.
• Train staff and manage reagents and supplies.

Skills

Scientific writing

Mouse genetics

Microscopy

Cell biology

Education

PhD or MD

Job description

## Postdoctoral Fellow-Arthroplasty Research LabApplylocations: New York, NYtime type: Full timeposted on: Posted Todayjob requisition id: JR2026-104768**How you move is why we’re here. Now more than ever.**Get back to what you need and love to do. The possibilities are endless... Now more than ever, our guiding principles are helping us in our search for exceptional talent - candidates who align with our unique workplace culture and who want to maximize the abundant opportunities for growth and success. If this describes you then let’s talk! HSS is consistently among the top-ranked hospitals for orthopedics and rheumatology by U.S. News & World Report. As a recipient of the Magnet Award for Nursing Excellence, HSS was the first hospital in New York City to receive the distinguished designation. Whether you are early in your career or an expert in your field, you will find HSS an innovative, supportive and inclusive environment.Working with colleagues who love what they do and are deeply committed to our Mission, you too can be part of our transformation across the enterprise.**Emp Status**Regular Full time**Work Shift****Compensation Range**The base pay scale for this position is $71,564.06 - $78,010.40. In addition, this position will be eligible for additional benefits consistent with the role. The salary of the finalist selected for this role will be determined based on various factors, including but not limited to: scope of role, level of experience, education, accomplishments, internal equity, budget, and subject to Fair Market Value evaluation. The hiring range listed is a good faith determination of potential compensation at the time of this job advertisement and may be modified in the future.# **What you will be doing****JOB DESCRIPTION**This project is primarily supported by an NIH R01 grant, with Dr. Matthew Greenblatt of Weill Cornell Medicine and Dr. Xu Yang of the Arthroplasty Research Laboratory at HSSRI serving as Co-PIs. We will develop critical foundational components of a novel approach for the regeneration of amputated limbs by transducing a specific population of autologous skeletal stem cells to induce a blastema-like state, followed by implantation at the amputation site to initiate regeneration of the missing limb.The candidate may also participate in other projects investigating the cellular and molecular mechanisms of orthopaedic implant osseointegration, including an ongoing project funded by the Department of Defense, with Dr. Xu Yang serving as PI.The postdoctoral fellow will report directly to Dr. Xu Yang for guidance on experimental design and research direction and will attend weekly laboratory meetings with Dr. Bostrom and Dr. Greenblatt.**YEARS OF EXPERIENCE REQUIRED** Candidates with a recent Ph.D. in Developmental Biology, Cell and Molecular Biology, or Neuroscience are highly desirable. **YEARS OF EXPERIENCE PREFERRED**Five years of postgraduate research experience in basic science. **PHYSICAL WORKING CONDITIONS** Continuously stand/walk to perform various biological experiments. **ENVIRONMENTAL WORKING CONDITIONS** Standard research lab. **HAZARDS OSHA** Category 1 Tasks that involve exposure to blood, body fluids, tissues, and other potentially infectious materials. **POSITION & UNIT ACCOUNTABILITIES*** + Design and execute experimental procedures and protocols involving cell and molecular biology techniques, tissue culture, histology, immunological assays, polarized and fluorescence microscopy, and animal models, including mouse breeding and genotyping. + Collect, analyze, and report experimental data to the Principal Investigator in a timely manner. + Maintain accurate and detailed records and databases of all laboratory work and experiments. + Apply standard scientific protocols to experiments; optimize and improve existing methods; and develop, establish, and validate new laboratory procedures. + Standardize and implement published procedures, evaluate innovative techniques, and develop new assays and protocols to support research objectives. + Maintain high assay performance and protocol reliability by conducting regular quality control and reproducibility assessments. + Compile, present, and discuss experimental findings and scientific insights with the Principal Investigator in a timely manner. + Maintain and monitor the proper use of laboratory equipment. + Troubleshoot and resolve experimental issues and equipment-related problems. + Draft, write, and edit scientific manuscripts, journal articles, abstracts, and progress reports related to the research. + Play an active role in laboratory meetings, departmental seminars, scientific presentations, and publications. + Manage research inventory records and coordinate the timely ordering of laboratory reagents and supplies. + Complete all required training related to laboratory activities in a timely manner, including C-14, animal use, hazardous materials handling, and laboratory safety training. + Participate in establishing job requirements and performance goals; perform duties at the expected level of competency and professionalism.**EDUCATION REQUIRED** PhD or MD **EDUCATION PREFERRED** PhD **CERTIFICATIONS/LICENSURE REQUIRED** N/A **CERTIFICATIONS/LICENSURE PREFERRED** N/A **SKILLS REQUIRED**Strong scientific writing skills, along with expertise in mouse genetics, light and confocal microscopy, and gold-standard cell and molecular biology techniques, are required. The candidate is expected to have one or more high-quality first-author publications in cell biology, disease mouse models, or related fields. The candidate should be highly motivated, productive, and interested in pursuing a research career.**SKILLS PREFERRED**Expertise in mouse models of wound/fracture healing and/or skeletal stem/progenitor cell biology is highly desirable.**Non-Discrimination Policy** Hospital for Special Surgery is committed to providing high quality care and skilled, compassionate, reliable service to our community in a safe and healing environment. Consistent with this commitment, Hospital for Special Surgery provides care, admits, and treats patients and provides all services without regard to age, race, color, creed, ethnicity, religion, national origin, culture, language, physical or mental disability, socioeconomic status, veteran or military status, marital status, sex, sexual orientation, gender identity or expression, or any other basis prohibited by federal, state, or local law or by accreditation standards.