Postdoctoral Fellow

City of Hope; Duarte (CA); On-site; USD 65,000 - 85,000; Full time

Job summary

City of Hope’s Beckman Research Institute invites applications for a Postdoctoral Fellow to join the van den Brink Laboratory, focusing on thymus biology, immune regeneration, and transplantation immunology using mouse models and human samples.

You will design independent projects, perform advanced flow cytometry and sequencing analyses, present at conferences, publish, and mentor trainees in a collaborative research environment.

Qualifications

• Ph.D., M.D., or MD/PhD in Immunology or related field.
• Demonstrated immunology, thymus biology, hematopoiesis, stem cell biology, transplantation biology, or cancer immunology experience.
• Strong flow cytometry, phenotyping, cell culture, molecular techniques, and/or mouse models.
• Desirable experience with bioinformatics, single-cell sequencing, spatial biology, or computational analysis.
• Peer‑reviewed publications and excellent communication skills.

Responsibilities

• Design, execute, and analyze independent research on thymic biology and immune regeneration.
• Utilize advanced approaches including flow cytometry, mouse models, and molecular biology.
• Analyze genomic, transcriptomic, and immunological data and present findings at meetings.
• Prepare manuscripts and contribute to grant applications and collaborations.
• Mentor graduate students and junior staff; collaborate across immunology and cancer biology programs.

Skills

Flow cytometry

Multicolor phenotyping

Cell culture

Molecular biology

Mouse models

Bioinformatics

Single-cell sequencing

Spatial biology

Computational analysis

Scientific communication

Education

PhD, MD, or MD/PhD in Immunology or related field

Tools

Bioinformatics tools

Job description

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life‑threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting‑edge research.

The van den Brink Laboratory is a leading research program focused on understanding the mechanisms that regulate immune system development, regeneration, and function, with a particular emphasis on thymus biology, hematopoietic stem cell transplantation, immune reconstitution, tolerance, and graft‑versus‑host disease. The Thymus Research Team investigates the cellular and molecular pathways that govern thymic regeneration and T cell development, with the goal of developing innovative therapies to restore immune competence in patients undergoing cancer treatment, hematopoietic cell transplantation, or other immune‑damaging interventions.

As a Postdoctoral Fellow, you will contribute to cutting‑edge basic and translational research projects using mouse models, human samples, and state‑of‑the‑art immunological, molecular, and computational approaches. You will work within a collaborative and multidisciplinary environment that integrates immunology, stem cell biology, oncology, and translational medicine to advance therapeutic strategies for immune regeneration.

As a successful candidate you will:

• Design, execute, and analyze independent research projects focused on thymic biology, T cell development, immune regeneration, and transplantation immunology.


• Utilize and develop advanced experimental approaches including multi‑parameter flow cytometry, cell sorting, mouse models, molecular biology techniques, and immune profiling assays.


• Analyze and interpret complex datasets, including genomic, transcriptomic, and immunological data.


• Present research findings at laboratory meetings, institutional seminars, and national/international scientific conferences.


• Prepare manuscripts for publication in peer‑reviewed journals and contribute to grant applications and collaborative research initiatives.


• Mentor graduate students, research technicians, and junior trainees as appropriate.


• Collaborate effectively with investigators and research teams across immunology, transplantation, and cancer biology programs.

Your qualifications should include:

• Ph.D., M.D., or M.D./Ph.D. in Immunology, Molecular Biology, Cell Biology, Biomedical Sciences, or a related field.


• Demonstrated research experience in immunology, thymus biology, hematopoiesis, stem cell biology, transplantation biology, cancer immunology, or a closely related discipline.


• Strong hands‑on experience with flow cytometry, multicolor immune phenotyping, cell culture, molecular biology techniques, and/or mouse models.


• Experience with bioinformatics, single‑cell sequencing analysis, spatial biology, or computational data analysis is desirable but not required.


• Proven scientific productivity demonstrated through peer‑reviewed publications and presentations.


• Excellent written and verbal communication skills and the ability to work both independently and collaboratively in a highly interactive research environment.


• Experience mentoring students or junior researchers is preferred.


• No specific license or certification required.

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.