Postdoctoral Fellow - Type 1 Diabetes Research

City of Hope; Duarte (CA); On-site; USD 55,000 - 70,000; Full time

Job summary

City of Hope's Beckman Research Institute invites applications for a Postdoctoral Fellowship in the AR-DMRI Department of Diabetes Immunology. The project centers on human Type 1 diabetes, miRNA biomarkers, pancreas pathology, and novel therapeutics using human samples from nPOD and donor tissue. Strong emphasis on translational research and clinical relevance.

The successful candidate will work under Dr. Alberto Pugliese, MD, contributing to data analysis and experimental workflows across flow

Qualifications

• PhD or M.D.
• Pre-doctoral experience/training in type 1 diabetes research desirable but not an absolute requirement
• Familiarity with computer software (Word, PowerPoint, Excel, databases) and basic statistical principles

Responsibilities

• You must have experience with flow cytometry, molecular biology techniques, cell culture, microscopy, tissue processing, immunohistochemistry, immunofluorescence, data analysis (gene expression data, flow cytometry data, etc). While our research is primarily focused on human specimens, animal studies are used on occasion.

Skills

Flow cytometry

Molecular biology

Cell culture

Microscopy

Tissue processing

Immunohistochemistry

Immunofluorescence

Data analysis

Education

PhD or M.D.

Job description

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Alberto Pugliese, MD in the AR-DMRI Department of Diabetes Immunology. The research is highly translational and primarily focused on human type 1 diabetes.

The major ongoing projects are investigating miRNA biomarkers, pancreas pathology, and novel therapeutics, also in the context of the analysis of live pancreas tissue from organ donors obtained from the Network for Organ Donors with Diabetes (nPOD), of which Dr. Pugliese is Executive Co-Director, and in future clinical trials. Upcoming studies are projected to include the analysis of samples from patients with type 1 diabetes participating in clinical trials, with trials expected to start in late 2023 and 2024. Additional studies involve analysis of samples from recipients of pancreas-kidney transplant in the context of recurrent type 1 diabetes.

As a successful candidate, you will:

• You must have experience with flow cytometry, molecular biology techniques, cell culture, microscopy, tissue processing, immunohistochemistry, immunofluorescence, data analysis (gene expression data, flow cytometry data, etc). While our research is primarily focused on human specimens, animal studies are used on occasion.

Your qualifications should include:

• PhD or M.D.
• Pre-doctoral experience/training in type 1 diabetes research desirable but not an absolute requirement
• Familiarity with computer software (Word, PowerPoint, Excel, databases) and basic statistical principles

Additional Information:

• For more information on nPOD please visit here: https://npod.org/
• For more information on the Arthur Riggs Diabetes & Metabolism Research Institute please visit here: https://www.cityofhope.org/research/riggs-institute/diabetes-milestones-and-history
• For more information on The Wanek Family Project for Type 1 Diabetes please visit here: https://www.cityofhope.org/research/riggs-institute/wanek-project/wanek-family-project-team

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.