Postdoctoral Associate, Sur Lab

Massachusetts Institute of Technology; Cambridge (MA); On-site; USD 65,000 - 75,000; Full time

Job summary

Massachusetts Institute of Technology (MIT) invites applications for a Postdoctoral Associate in the SUR Lab. The selected candidate will join the laboratory of Mriganka Sur to explore the molecular mechanisms underlying Rett Syndrome and other neurodevelopmental disorders using human stem cells.

Responsibilities include maintaining pluripotent stem cells, differentiating them into brain organoids and 2D cultures, and identifying molecular targets.

Qualifications

• Research experience in molecular biology and neurodevelopmental disorders.
• Experience with pluripotent stem cells and differentiation protocols.
• Data analysis and literature synthesis skills.

Responsibilities

• Conduct experiments to study molecular mechanisms of Rett Syndrome using human pluripotent stem cells, brain organoids, and 2D cultures.
• Identify and validate molecular and cellular targets; analyze data and generate results.
• Collaborate with other groups and core facilities; plan and perform experiments with quantitative data collection.

Job description

POSTDOCTORAL ASSOCIATE, SUR LAB, Picower Institute for Learning and Memory, to join the laboratory of Mriganka Sur, whose goal is to discover fundamental mechanisms of brain wiring and processing and how they go awry in disorders of brain development. The postdoctoral associate is responsible for conducting research to study the molecular mechanisms of Rett Syndrome. They will use human stem cells, combined molecular and microscopy technologies, to study the early mechanisms of Rett Syndrome and other neurodevelopmental disorders in vitro. Responsibilities include performing human pluripotent stem cell maintenance and differentiation into brain organoids and 2D cultures; identifying and validating molecular and cellular targets, working independently to generate and analyze data, and working with collaborating research groups and core facilities. Conducting this research involves planning and performing experiments, and collecting and analyzing data using quantitative techniques, which requires a unique background and combination of skills in biological methods.

The full job description is available, here: https://acrobat.adobe.com/id/urn:aaid:sc:VA6C2:a2067ba8-1571-4339-9d85-24a99b2ca4e9