Postdoctoral Associate

Upstate Medical University; United States; On-site; USD 70,000 - 90,000; Full time

Job summary

A leading research university in the United States is seeking a Neuroscience researcher with a PhD. Responsibilities include conducting advanced techniques in cerebral surgery, neurobehavioral testing, and data analysis. Ideal candidates will have experience in neurodegenerative diseases and molecular biology. Strong communication skills are essential for this role.

Responsibilities

• Conduct tissue gene expression and protein quantification.
• Perform gene knock-in and knock-down experiments.
• Use live cell imaging techniques.
• Analyze research data and write manuscripts.

Skills

Basic skills in cerebral surgery for small animals

Perform neurobehavioral testing

Execute irradiation and bone marrow isolation

Inject cells or drugs intravenously

Isolate and culture neurons and stem cells

Analyze research data

Communication skills

Education

PhD degree in Neuroscience or a related field

Job description

Job Summary

• Have basic skills in cerebral surgery for small animals, including experience in creating mouse models of traumatic brain injury and skull windows for live brain imaging.
• Perform neurobehavioral testing such as water maze, Y maze, and novel object recognition in mice.
• Execute irradiation, bone marrow isolation, bone marrow transplantation, blood collection, flow cytometry, and immunohistochemistry.
• Inject cells or drugs intravenously or intracerebrally.
• Isolate and culture neurons, bone marrow stem cells, and monocytes/microglial cells.
• Conduct tissue gene expression and protein quantification, cell adhesion and cell–cell interaction studies, and identify cell signalling pathways.
• Quantify gene expression and protein production, perform gene knock‑in and knock‑down experiments.
• Use live cell imaging, two‑photon live brain imaging, and confocal imaging.
• Isolate and identify microvesicles and exosomes.
• Examine neurite outgrowth, synaptic formation, maturation, cell adhesion and migration, and cell‑cell interaction.
• Analyze research data and write research manuscripts.
• Have good communication skills.

Minimum Qualifications

• A PhD degree in Neuroscience or a related field.

Preferred Qualifications

• Experience in neurodegenerative diseases/neurological disorders, stem cell biology, and molecular biology with related publications.

Work Days

• Monday‑Friday