Postdoctoral Associate - Stanley Center

Broad Institute; Cambridge (MA); On-site; USD 60,000 - 100,000; Full time

Job summary

An established industry player seeks a dedicated researcher to explore the intricate mechanisms of psychiatric disorders. This role involves utilizing advanced techniques like in vivo recordings and optogenetic manipulations to uncover the underlying causes of behavioral and neurophysiological deficits in rodent models. The successful candidate will contribute to groundbreaking research aimed at developing novel therapeutics, while collaborating within a dynamic team. If you are passionate about neuroscience and eager to make a significant impact in the field, this opportunity is perfect for you.

Qualifications

• Ph.D. in Neuroscience or related field with first author publications.
• Solid training in stereotaxic surgical procedures and optogenetics.

Responsibilities

• Investigate mechanisms underlying behavioral deficits in rodent models.
• Utilize in vivo recordings and pharmacology to analyze disease etiology.

Skills

Neuroscience

Pharmacology

Optogenetics

Chemogenetics

Stereotaxic Surgical Procedures

In Vivo Recordings

Behavioral Testing

Communication Skills

Education

Ph.D. in Neuroscience

Ph.D. in Pharmacology

Job description

Description & Requirements

OVERALL RESPONSIBILITY

The long-term research goal of the Pan lab is to understand the molecular, cellular and circuit mechanisms underlying psychiatric disorders and develop novel therapeutics to treat these disorders.

The lab uses a broad spectrum of techniques such as in vitro electrophysiology, ex vivo and in vivo neurophysiology, genetic and molecular manipulation, biochemistry, cell biology, as well as behavioral testing.

The Broad Institute is a leading biomedical research institute, known for its cutting-edge technology/research and highly collaborative research environment.

The mission of the Stanley Center for Psychiatric Research at the Broad Institute is to discover novel therapeutics to ameliorate the burden of major psychiatric and neurological illnesses.

• Successful candidate will investigate novel mechanisms underlying behavioral and neurophysiological deficits in rodent models of diseases.

• The candidate will utilize an array of techniques including in vivo recordings, pharmacology, chemo- and optogenetic manipulations to analyze the role of genetic and environmental perturbation (such as sleep deprivation and stress) on the disease etiology and pathogenesis.

• The researcher will be responsible for communicating results to the scientific community through conference presentations and publications, and within Broad Institute internal communications.

QUALIFICATIONS

• Ph.D. in Neuroscience, pharmacology or related field with proven record of first author publications (or in press) in peer-reviewed journals.

• Solid training in stereotaxic surgical procedures and (including local injections or implantations) optogenetics/chemogenetics manipulations is required. Demonstrated technical proficiency in LFP and/or single unit in vivo recordings of live animals is highly desired.

• Candidate with experience in sleep research are highly encouraged to apply.

• Outstanding personal initiative and communication skills, to work in a collaborative environment.