Postdoctoral Associate (L,P,S)

Mississippi State University; Mississippi; On-site; USD 55,000 - 75,000; Full time

Job summary

Mississippi State University invites applications for a postdoctoral associate focusing on the synthesis of organic fluorophores and cellular culturing. The position emphasizes developing new dye probes and validating their performance in biological systems.

The successful candidate will design multistep syntheses, work with mammalian cell culture, and apply fluorescence and confocal microscopy to assess dye uptake and imaging.

Qualifications

• PhD in Organic Chemistry or related field.
• Experience with multistep organic synthesis and compound characterization (NMR, MS, chromatography, etc.).
• Experience with mammalian cell culture and sterile laboratory techniques.
• Excellent written and oral communication skills.

Responsibilities

• Design and synthesize functional organic fluorophores and related molecular probes.
• Develop and optimize synthetic methodologies for dye functionalization.
• Culture and maintain mammalian cell lines under sterile conditions.
• Evaluate dye uptake, localization, cytotoxicity, and imaging performance in cultured cells.
• Perform fluorescence microscopy, confocal microscopy, flow cytometry, and related cellular imaging techniques.
• Analyze experimental data and correlate molecular structure with biological performance.
• Mentor graduate and undergraduate researchers in both synthetic chemistry and cell biology.
• Prepare manuscripts, present research findings at scientific conferences, and assist with proposal development.

Skills

Organic synthesis

Mammalian cell culture

Fluorophore chemistry

Fluorescence imaging

Education

PhD in Organic Chemistry or related field

Tools

NMR

MS

Chromatography

Microscopy

Job description

Position Function:

Vacancy for a postdoctoral associate focused on the synthesis oforganic fluorophores and cellular culturing

Salary Grade

For salary grade UC, these positions are \"Unclassified\" and salaryranges are determined by the hiring department.

Department Profile:

For more information on the Department of Chemistry, please visitwww.chemistry.msstate.edu

Essential Duties and Responsibilities:

• Design and synthesize functional organic fluorophores and relatedmolecular probes.


• Develop and optimize synthetic methodologies for dyefunctionalization.


• Culture and maintain mammalian cell lines under sterileconditions.


• Evaluate dye uptake, localization, cytotoxicity, and imagingperformance in cultured cells.


• Perform fluorescence microscopy, confocal microscopy, flowcytometry, and related cellular imaging techniques.


• Analyze experimental data and correlate molecular structure withbiological performance.


• Mentor graduate and undergraduate researchers in both syntheticchemistry and cell biology.


• Prepare manuscripts, present research findings at scientificconferences, and assist with proposal development.

Minimum Qualifications:

• A Ph.D. in Organic Chemistry, Chemical Biology, MedicinalChemistry, Biochemistry, or a closely related field.


• Demonstrated expertise in multistep organic synthesis andcompound characterization (NMR, MS, chromatography, etc.).


• Experience with mammalian cell culture and sterile laboratorytechniques.


• Excellent written and oral communication skills


• Ability to work independently while collaborating effectivelywithin a multidisciplinary research team.

Preferred Qualifications:

• Fluorescent probe or dye synthesis.


• Confocal or fluorescence microscopy.


• Flow cytometry.


• Cell viability and cytotoxicity assays.


• Image analysis software (ImageJ/Fiji or equivalent).


• Experience with NIR/SWIR imaging, molecular imaging, or chemicalbiology.

Knowledge, Skills, and Abilities:

Excellent written and verbal communication skills.

Proven ability to work independently and as part of a team.

Working Conditions and Physical Effort

Regularly involves lifting and bending. Often exposed to one ormore elements such as heat, cold, noise, dust, dirt, chemicals,etc.

Restricted Clause:

Position is contingent upon continued availability offunding.

Equal Employment Opportunity Statement:

Mississippi State University is an equal opportunity institution.Discrimination is prohibited in university employment, programs oractivities based on race, color, ethnicity, sex, pregnancy,religion, national origin, disability, age, sexual orientation,genetic information, status as a U.S. veteran, or any other statusto the extent protected by applicable law. Questions about equalopportunity programs or compliance should be directed to the Officeof Civil Rights Compliance, 231 Famous Maroon Band Street, P.O.6044, Mississippi State, MS 39762, [phone].

What do I do if I need an accommodation?

In compliance with the ADA Amendments Act (ADA), if you have adisability and would like to request an accommodation in order toapply for a position with Mississippi State University, pleasecontact the Department of Human Resources Management at tel: [phone] or [e-mail] .

If you have any questions regarding this policy, contact theDepartment of Human Resources Management at [phone] or [e-mail] . Uponrequest, sections of this job listing are available in large print,and readers are available to assist the visually impaired.