Postdoctoral Associate (Dr. Weiran Feng)

Temple University Health System, Inc.; Philadelphia (Philadelphia County); On-site; USD 50,000 - 70,000; Full time

Job summary

Rejoignez le groupe de recherche financé par le NIH au Fox Chase Cancer Center pour un poste postdoctoral. Vous étudiez les mécanismes de développement du cancer de la prostate avec des modèles avancés tout en contribuant à des découvertes sur la résistance aux thérapies. Collaboration avec des experts en épigénétique et en biologie moléculaire pour former un réseau de recherche solide.

Qualifications

• PhD nécessaire, expert en biologie du cancer et épigénétique.
• Expérience dans l'ingénierie CRISPR et des techniques expérimentales demandée.
• Compétences en communication écrite et verbale essentielles.

Responsibilities

• Étudier les mécanismes de développement et de résistance du cancer de la prostate.
• Conduire des recherches de manière indépendante et collaborative.
• Publier des manuscrits évalués par des pairs.

Skills

Cancer biology

Epigenetics

CRISPR engineering

Molecular biology

Computational biology

Experimental techniques

Excellent communication skills

Education

PhD in Physical or Biological Sciences

Job description

A Postdoctoral position is available in 2025 for a highly-motivated, enthusiastic individual in the NIH-funded group of Dr. Weiran Feng in the Cancer Epigenetics Institute, Fox Chase Cancer Center. Opening in Jan 2025, the Feng group will be studying the mechanisms of prostate cancer development and therapy resistance. We leverage state-of-the-art animal and organoid models, genetic engineering, functional genetics and genomic approaches to investigate the molecular mechanisms driving prostate cancer initiation, progression, and therapy resistance. Our research explores both cancer cell-intrinsic pathways and the cell-cell interactions within the tumor microenvironment. Our overarching goal is to make mechanistic discoveries that drive novel therapy development to improve clinical benefits.

Interested applicants should be highly dedicated, enthusiastic and have experience publishing peer reviewed manuscripts. Expertise in cancer biology, epigenetics, CRISPR engineering, animal work, molecular biology, and computation biology is preferred. In addition, applicants should possess excellent written and verbal communication skills, and the ability to conduct research both independently and collaboratively.

Dr. Weiran Feng received PhD training in molecular and cell biology and genome editing with Dr. Maria Jasin at MSKCC. He then received postdoctoral training in organoid technology and cancer genetics with Dr. Charles Sawyers at MSKCC, with a focus on prostate cancer initiation. His work: i) developed an efficient approach to CRISPR edit organoids and freshly isolated primary cells for rapid in vivo functional interrogation; ii) discovered a cell context dependency and vulnerabilities of ERG, the most prevalent oncogenic transcription factor in prostate cancer. He co-authored 11 manuscripts, including 4 first-author research papers in top journals, and received awards including an Olayan Fellowship Award, DoD Early Investigator Research Award, PCF Young Investigator Award, and an NCI-K99/R00 Award.

The Feng laboratory is a member of the Cancer Epigenetics Institute (CEI) at Fox Chase. CEI offers trainees exceptional access to global epigenetics leaders and industry experts. CEI hosts an annual symposium featuring discussions on the latest advances, poster sessions, and travel awards. Trainees also present their research to colleagues within CEI and across FCCC. The institute is committed to enhancing each trainee’s networking opportunities and exposure to cutting-edge science, supporting optimal career development that is suited for you.

As one of the four original cancer centers to receive comprehensive designation from the National Cancer Institute (NCI), Fox Chase has been at the forefront of cancer research for almost 90 years and is home to world-class clinicians, scientists, and research facilities. Moreover, Fox Chase is part of the rich scientific and biotech environment in the Philadelphia region and has a strong record of career placement in academia, industry, as well as other scientific positions.

Education
Doctorate Degree : PhD in Physical or Biological Sciences (MD acceptable in lieu of PhD) (Required)

Experience
General experience and college level knowledge of key scientific concepts (Required)
General experience with general lab techniques (Required)
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Your Tomorrow is Here!

Temple Health is a dynamic network of outstanding hospitals, specialty centers, and physician practices that is advancing the fight against disease, pushing the boundaries of medical science, and educating future healthcare professionals. Temple Health consists of Temple University Hospital (TUH), Fox Chase Cancer Center, TUH-Jeanes Campus, TUH-Episcopal Campus, TUH-Northeastern Campus, Temple Physicians, Inc., and Temple Transport Team. Temple Health is proudly affiliated with the Lewis Katz School of Medicine at Temple University.

To support this mission, Temple Health is continuously recruiting top talent to join its diverse, 10,000 strong workforce that fosters a healthy, safe and productive environment for its patients, visitors, students and colleagues alike. At Temple Health, your tomorrow is here!

Equal Opportunity Employer/Veterans/Disabled

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Your Tomorrow is Here!

As one of the first cancer hospitals in the country, Fox Chase Cancer Center has been a national leader in cancer treatment, research, and prevention for more than 100 years. Fox Chase Cancer Center, part of the Temple University Health System, is committed to providing the best treatment options for our patients, and delivering that care with compassion.

At Fox Chase, we consider defeating cancer to be our calling. Our unique culture allows employees to work collaboratively with a single, shared focus, regardless of which department they’re in.

It’s essential for us to recruit not only the best talent in hospital care, but hire well-qualified prospective employees who are committed to serving our patients with the passion and excellence for which Fox Chase is known. Apply today to be part of the future of prevailing over cancer.

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