Postdoc: T Cell Immunology & Tissue Microenvironment

Biohub; New York (NY); On-site; USD 93,000 - 150,000; Full time

Benefits offered by this job

Relocation support

401(k) employer match

Volunteer time off

Job summary

Biohub seeks a Postdoctoral Fellow or Scientist I in T cell biology and tissue immunology at its New York site. The role investigates how T cells interact with tissue microenvironments to shape immune responses in health and disease, using cutting-edge genomics, spatial transcriptomics, and in vivo models.

The successful candidate will design independent projects, mentor junior researchers, and contribute to multidisciplinary efforts across immunology, genomics, and technology development.

Qualifications

• PhD required in molecular biology, bioengineering, genetics, cell biology, immunology, or related field.
• 3+ years of demonstrated impact in experimental molecular and cellular biology.
• 2+ years post-PhD experience for Scientist position.
• Experience with mouse models and tissue processing.
• Molecular cloning, genetic engineering, or perturbation approaches.
• Designing, optimizing, troubleshooting complex workflows.
• Independent experimental design, execution, and interpretation.
• Strong communication and collaboration skills.
• Interest in engineering and functional genomics to study complex systems.

Responsibilities

• Investigate cellular and molecular mechanisms regulating immune responses in tissue microenvironments.
• Design and perform in vivo experiments using mouse models.
• Characterize immune cell differentiation, function, and interactions.
• Apply single-cell sequencing, spatial transcriptomics, and genetic perturbation methods.
• Develop hypotheses to understand how immune cells and tissues shape each other.
• Collaborate across Biohub to integrate multi-omics datasets.
• Plan, execute, and analyze experiments independently.
• Present findings at meetings and prepare manuscripts.
• Mentor junior researchers and advance lab scientific direction.

Skills

Post-PhD experience (Scientist level)

Mouse models

Tissue processing

Molecular cloning

Genetic perturbation

Experiment design & troubleshooting

Independent work & interpretation

Communication & collaboration

Engineering & functional genomics

Pooled CRISPR screens

In vivo perturbations

Single-cell RNA sequencing

Spatial transcriptomics

Viral vector engineering

Flow cytometry

High-dimensional data analysis

Education

PhD in molecular biology / bioengineering / genetics / cell biology / immunology

Tools

Genetic engineering tools

Genomic perturbation platforms

Job description

Biohub seeks a Postdoctoral Fellow or Scientist I in T cell biology and tissue immunology at its New York site. The role investigates how T cells interact with tissue microenvironments to shape immune responses in health and disease, using cutting-edge genomics, spatial transcriptomics, and in vivo models.

The successful candidate will design independent projects, mentor junior researchers, and contribute to multidisciplinary efforts across immunology, genomics, and technology development.