Postdoc: Systems Immunology & Computational Biology

Commonwealth of VA Careers; Charlottesville (VA); On-site; USD 55,000 - 65,000; Full time

Job summary

The Woodfolk Laboratory at the University of Virginia School of Medicine seeks a Postdoctoral Research Associate with expertise in systems immunology and computational biology. The role focuses on integrating experimental and computational approaches to define immune states and pathways in allergy and respiratory disease.

The successful candidate will generate and analyze high-dimensional data, including multiparameter flow cytometry and transcriptomics, and collaborate to translate findings

Qualifications

• Doctoral degree in immunology, computational biology, bioinformatics, systems biology, or related field.
• Strong knowledge of immunology.
• Extensive coding and computational experience.
• Experience analyzing high-dimensional flow cytometry and/or transcriptomics datasets.
• Experience developing or modifying computational pipelines for biological data.
• Strong quantitative and analytical skills, including statistics and visualization.
• Ability to work independently and in multidisciplinary teams.
• Strong scientific writing and communication skills.
• Experience with single-cell RNA sequencing, CITE-seq, TCR sequencing, or multimodal single-cell technologies.
• Experience applying machine learning or network analysis to immunological questions.
• Research experience in immune-mediated diseases.

Responsibilities

• Design and implement systems immunology studies using high-dimensional immune profiling and transcriptomics.
• Generate, process, and analyze multiparameter flow cytometry data to characterize immune cell populations and states.
• Analyze bulk and single-cell transcriptomic datasets and integrate with phenotypes.
• Develop computational pipelines for high-dimensional data analysis.
• Apply statistical and machine-learning methods to identify immune signatures and pathways.
• Collaborate to develop hypotheses, design experiments, and validate findings.
• Contribute to manuscript preparation, grant development, and scientific presentations.
• Mentor students and foster an interdisciplinary research environment.

Skills

Immunology

Computational biology

High-dimensional data analysis

Flow cytometry

Transcriptomics

Machine learning

Statistical analysis

Scientific writing

Independent and collaborative work

Single-cell technologies

Education

PhD in immunology or computational biology

Tools

Python

R

Workflow/ pipelines

Job description

The Woodfolk Laboratory at the University of Virginia School of Medicine seeks a Postdoctoral Research Associate with expertise in systems immunology and computational biology. The role focuses on integrating experimental and computational approaches to define immune states and pathways in allergy and respiratory disease.

The successful candidate will generate and analyze high-dimensional data, including multiparameter flow cytometry and transcriptomics, and collaborate to translate findings