Postdoc: Single-Molecule Imaging & Gene Regulation

The Pennsylvania State University; Ferguson Township (PA); On-site; USD 65,000 - 90,000; Full time

Job summary

The Pennsylvania State University invites applications for a Postdoctoral Position in the lab of Dr. Manyu Du. Work focuses on how transcription machineries and regulatory DNA elements organize in 3D to regulate gene expression using advanced imaging and biophysical approaches.

You will study transcriptional condensates in mouse cells, employing single-molecule imaging, lattice light sheet microscopy, and sequencing approaches to elucidate genome organization and regulation in health and disease.

Qualifications

• PhD in molecular biophysics, biochemistry or a related discipline.
• Independent, creative, and highly motivated post-doctoral scientist who can work effectively in a team.
• Strong communication skills and ability to collaborate across disciplines.

Responsibilities

• Investigate the behavior of individual molecules and bio-molecular condensates in living cells.
• Develop and apply imaging and computational methods to visualize dynamic molecule clusters during gene expression.

Skills

Single-molecule imaging

Live-cell imaging

Fluorescence imaging

Quantitative modeling

Biochemistry background

Communication skills

Team collaboration

Education

PhD in molecular biophysics or biochemistry

Tools

Lattice light sheet microscopy

Computational methods

Biophysical data analysis

Job description

The Pennsylvania State University invites applications for a Postdoctoral Position in the lab of Dr. Manyu Du. Work focuses on how transcription machineries and regulatory DNA elements organize in 3D to regulate gene expression using advanced imaging and biophysical approaches.

You will study transcriptional condensates in mouse cells, employing single-molecule imaging, lattice light sheet microscopy, and sequencing approaches to elucidate genome organization and regulation in health and disease.