Postdoc Research Scholar- Nascone-Yoder Lab

NC State University; Raleigh (NC); On-site; USD 60,000 - 65,000; Full time

Job summary

NC State University seeks a Postdoc Research Scholar in the Nascone-Yoder Lab to lead research on anatomical left-right asymmetry. You will independently investigate cellular mechanisms of organ morphogenesis using advanced gene editing and imaging techniques.

The ideal candidate will have a Ph.D. in a relevant field, strong publication record, and significant experience in microscopy and animal model handling, contributing to ongoing research projects and collaborations.

Qualifications

• Expertise in gene editing, immunostaining techniques.
• Extensive experience in in vivo research and animal model handling.
• Strong background in microscopy and image analysis.

Responsibilities

• Conduct independent research on anatomical left-right asymmetry.
• Design and analyze complex biological experiments.
• Prepare and produce manuscripts for peer-reviewed journals.

Skills

Advanced Research Methodologies

Microscopy and Image Processing

Gene Editing

Molecular Biology

Data Analysis

Education

Ph.D. in Developmental/Molecular Biology or related field

Tools

Confocal Microscopy

CRISPR

Job description

Postdoc Research Scholar – Nascone-Yoder Lab

Department ID 194001 - Department of Molecular Biomedical Sciences

Position Overview

The Postdoctoral Researcher will conduct independent research focusing on the development of anatomical left-right asymmetry. Specifically, the incumbent will investigate the cellular and molecular mechanisms of left-right asymmetric organ morphogenesis within the developing digestive tract. Research methodologies will utilize advanced gene misexpression strategies (CRISPR/morpholino oligonucleotides), transcriptomics (bulk and/or spatial), 3D imaging modalities (nano‑CT), and/or computational modeling (CompuCell3D).

Core Competencies & Responsibilities

• Project Leadership: Demonstrated ability to independently lead, manage, and execute complex research projects while working effectively within an interdisciplinary team environment.
• Communication & Collaboration: Excellent oral and written communication skills, with a proven track record of successful scientific collaboration.

Technical Expertise & Preferred Qualifications

• Advanced Research Methodologies: Demonstrated expertise in microscopy, image processing/analysis, gene editing, immunostaining, and/or molecular biology.
• Scholarly Output: A strong record of publication in peer‑reviewed scientific journals, reflecting the ability to synthesize and disseminate research findings.

Research Design and Execution

• Independent Experimentation: Independently design and conduct research experiments to investigate developmental processes.
• Advanced Methodologies: Utilize advanced technical methodologies, including gene expression analysis, cell lineage tracing, and manipulation of genetic pathways.
• Model Organism Care: Manage, work with, and care for living model organisms (e.g., mouse, Xenopus) as required by research protocols.

Data Analysis and Interpretation

• Technical Analytics: Analyze complex experimental data using advanced techniques such as microscopy imaging and bioinformatics.
• Data Visualization: Generate high‑quality figures, charts, and diagrams to clearly present research data.
• Results Interpretation: Interpret experimental results to draw meaningful, data‑driven conclusions about the mechanisms of development.

Publication and Dissemination

• Manuscript Production: Prepare and draft scientific manuscripts for publication in peer‑reviewed journals, managing data presentation, discussion text, and subsequent revisions.
• Research Presentation: Disseminate research findings at national and international conferences, as well as within internal collaborative networks.
• Intra‑Lab Support: Collaborate with laboratory colleagues and contribute to ongoing projects involving alternative organ systems.
• Cross‑Disciplinary Partnership: Partner with researchers across scientific disciplines to exchange expertise and advance shared research aims.

Other Work and Responsibilities

• Grant Writing Support: Support the development of institutional and federal grant proposals by conducting literature reviews and drafting experimental design sections.
• Professional Development: Attend scientific conferences or technical courses to present findings and actively expand research skill sets.
• Laboratory Management & Mentorship: Maintain accurate laboratory records, manage research supply inventories, and mentor or train junior researchers and undergraduate students.

Work Schedule

9:00am-5:00pm Monday-Friday; Occasional Evening and Weekend Hours

Requirements and Preferences

• Ph.D. in Developmental/Molecular Biology: Or a closely related scientific field.
• In Vivo Research & Animal Model Handling: Extensive experience with common developmental biology models, small animal handling, and specialized care.
• Advanced Microscopy & Image Analysis: Hands‑on experience with confocal microscopy, image processing, and morphometrics.
• Molecular & Genetic Proficiency: Demonstrated expertise in gene editing, misexpression, and immunostaining techniques.
• Lab Operations, Autonomy, & Teamwork: Strong knowledge of compliance/data management, with a proven ability to lead projects independently and collaborate effectively.

Valid NC Driver's License

No

Recruitment Details

Anticipated Hiring Range $60,000-$65,000

Equal Employment Opportunity Statement

NC State University is an equal opportunity employer. All qualified applicants will receive equal opportunities for employment without regard to age, color, disability, gender identity, genetic information, national origin, race, religion, sex (including pregnancy), sexual orientation, and veteran status. The University encourages all qualified applicants, including protected veterans and individuals with disabilities, to apply. Individuals with disabilities requiring disability‑related accommodations in the application and interview process are welcome to contact 919‑513‑0574 to speak with a representative of the Office of Equal Opportunity.

Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit.

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