Postdoc: Lysosomal Biology & Neuroprotection Scientist

BioSpace; Boston (MA); On-site; USD 70,000 - 95,000; Full time

Job summary

Lilly is seeking a highly motivated Postdoctoral Scientist to join the Lilly Gene Therapy (LGT) organization in Boston, focused on lysosomal biology and metabolic regulation. You will design and execute LC-MS–based omics assays and collaborate across teams, contributing to mechanistic insights into chronic inflammation and neuroprotection.

The role involves hands-on preclinical mouse work, cross-functional collaboration, and publication in peer‑reviewed journals.

Qualifications

• PhD in Biochemistry, Neuroscience, Molecular Biology, Cell Biology, or closely related life sciences.
• Deep expertise with LC-MS–based lipidomics, metabolomics, and proteomics profiling.
• Experience with immunoproteomics, ELISA, or ligand-binding (LBA) assays and PCR/qPCR/ddPCR for transcript quantification.

Responsibilities

• Lead LC-MS–based multi-omics bioanalysis across peripheral, pulmonary, and CNS tissues.
• Design and execute immunoproteomics, ELISA, and LBA assays to quantify biomarkers of lysosomal health.
• Integrate lipidomic, proteomic, and transcriptomic readouts into a unified framework.
• Collaborate with cross-functional teams and external CROs; provide scientific oversight.
• Present findings via presentations and peer‑reviewed publications.

Skills

LC-MS–based lipidomics

Metabolomics

Proteomics profiling

Immunoproteomic

ELISA

Ligand-binding assay (LBA)

PCR/qPCR/ddPCR

Education

PhD in Biochemistry, Neuroscience, Molecular Biology or Cell Biology

Tools

LC-MS/MS

Job description

Lilly is seeking a highly motivated Postdoctoral Scientist to join the Lilly Gene Therapy (LGT) organization in Boston, focused on lysosomal biology and metabolic regulation. You will design and execute LC-MS–based omics assays and collaborate across teams, contributing to mechanistic insights into chronic inflammation and neuroprotection.

The role involves hands-on preclinical mouse work, cross-functional collaboration, and publication in peer‑reviewed journals.