Postdoc: In Vivo Pharmacology for Colorectal Cancer

University of Colorado; Aurora (CO); On-site; USD 63,000 - 77,000; Full time

Job summary

University of Colorado Anschutz Medical Campus is offering a full-time Postdoctoral Fellow position in the Department of Pharmaceutical Sciences. The role focuses on in vivo pharmacology, preclinical oncology, and mouse therapeutic efficacy studies for colorectal cancer, with CDX/PDX models and collaboration with Onconaut Therapeutics Inc.

The fellow will design and perform studies in mouse models, monitor tumor growth, administer treatments, collect samples, and contribute to publications and

Qualifications

• PhD, MD, DVM, or equivalent doctorate in pharmacology, pharmaceutical sciences, cancer biology, molecular or cellular biology, translational biomedical sciences, or closely related field.
• Hands-on experience designing and conducting mouse in vivo pharmacology or therapeutic efficacy studies.
• Experience with mouse tumor xenograft models, including CDX and patient-derived xenografts.
• Proficiency in mouse handling, restraint, health monitoring, and animal welfare procedures.
• Experience administering drugs to mice by oral gavage, IP, and IV routes.
• Ability to collect, analyze, interpret, and document data from animal studies independently.

Responsibilities

• Design, plan, and execute in vivo pharmacology and efficacy studies in mouse models of colorectal cancer.
• Establish CDX and PDX studies, including implantation, growth monitoring, randomization, treatment, and endpoints.
• Administer investigational therapeutics via PO, IP, and IV with repeated-dose regimens.
• Perform mouse handling, health monitoring, weight, and humane endpoint assessments.
• Collect tissues, necropsy, tissue processing, and support histologic or molecular analyses.
• Analyze data, maintain study records, and prepare figures, reports, and manuscripts.
• Collaborate with academic and industry investigators to develop and troubleshoot protocols.

Skills

In vivo pharmacology

Preclinical oncology

CDX/PDX models

Mouse handling

Data analysis

Scientific writing

Independent troubleshooting

Education

PhD/MD/DVM or equivalent in pharmacology or related field

Job description

University of Colorado Anschutz Medical Campus is offering a full-time Postdoctoral Fellow position in the Department of Pharmaceutical Sciences. The role focuses on in vivo pharmacology, preclinical oncology, and mouse therapeutic efficacy studies for colorectal cancer, with CDX/PDX models and collaboration with Onconaut Therapeutics Inc.

The fellow will design and perform studies in mouse models, monitor tumor growth, administer treatments, collect samples, and contribute to publications and