Postdoc: Human Cortical Development & Organoids

Washington University in St. Louis; St. Louis (MO); Presencial; USD 60.000 - 85.000; Jornada completa

Descripción de la vacante

Washington University in St. Louis in St. Louis, MO seeks a Postdoctoral Research Associate to lead new studies on human cortical development and neurodevelopmental disorders.

You will leverage patient-derived iPSCs, organoids, and assembloids with multi-omics, hi-content imaging, and HD-MEA to uncover transcriptional and epigenetic regulation of interneuron and excitatory neuron specification. The role involves independent project leadership, collaboration with a multidisciplinary team,

Formación

• Ph.D. in neuroscience, molecular biology, stem cell biology, or a related field.
• Strong publication record in cellular neurobiology, genomics, or stem cell models.
• Experience with hPSC models and directed differentiation into relevant lineages in 2-D and 3-D (organoid) culture.
• Experience with chromatin profiling (e.g., CUT&RUN/CUT&Tag) to define chromatin state and transcriptional regulation.
• Experience with high-content imaging and functional phenotyping.

Responsabilidades

• Designs and executes experiments using hPSC models, organoids, and assembloids.
• Analyzes multi-omics datasets and integrates results with team workflows.
• Presents work at meetings and conferences; contributes to manuscripts and grants.
• Mentors trainees and maintains accurate research records.

Conocimientos

Collaboration

Data analysis

Experimentation

Scientific writing

Educación

Ph.D. in neuroscience or related field

Herramientas

CUT&RUN / CUT&Tag

RNA-seq

High-content imaging

HD-MEA

Descripción del empleo

Washington University in St. Louis in St. Louis, MO seeks a Postdoctoral Research Associate to lead new studies on human cortical development and neurodevelopmental disorders.

You will leverage patient-derived iPSCs, organoids, and assembloids with multi-omics, hi-content imaging, and HD-MEA to uncover transcriptional and epigenetic regulation of interneuron and excitatory neuron specification. The role involves independent project leadership, collaboration with a multidisciplinary team,