Postdoc - Chakrapani lab

Case; Cleveland (OH); On-site; USD 55,000 - 63,000; Full time

Benefits offered by this job

Health benefits

Life insurance

Employee assistance program

Job summary

Case Western Reserve University is seeking a postdoctoral researcher in Pharmacology to study ion channel complexes' structure, function, and pharmacology. The lab, led by Dr.

Sudha Chakrapani, uses cryo-EM, Cryo-ET, electrophysiology, and other biophysical methods to understand fast synaptic transmission. The position offers NIH-funded support, access to advanced structural biology infrastructure, and opportunities for professional growth, with competitive benefits and a collaborative

Qualifications

• PhD or expected soon in physiology, structural biology, biochemistry, pharmacology, or closely related discipline.
• 0-4 years of postdoctoral experience.
• Experience in patch-clamp electrophysiology, membrane protein biochemistry, cellular neuroscience, and Cryo-EM preferred.
• Excellent oral and written communication.
• Strong project management and scientific writing skills.

Responsibilities

• Investigate structure, function, and pharmacology of ion channel complexes.
• Utilize multidisciplinary approaches including cryo-EM, Cryo-ET, electrophysiology, and biophysical methods.
• Collaborate within a well-equipped research environment and contribute to NIH-funded projects.

Skills

Patch-clamp electrophysiology

Biochemistry

Cellular neuroscience

Oral and written communication

Project management

Scientific writing

Education

PhD degree in physiology/structural biology/biochemistry/pharmacology or closely related

Tools

Cryo-EM

Cryo-ET

Electrophysiology

Job description

Case Western Reserve University: POSTDOCTORAL: School of Medicine (PD): Pharmacology (PD)

Open Date

Oct 18, 2026

Description

The laboratory of Dr. Sudha Chakrapani in the Department of Pharmacology at Case Western Reserve University is actively seeking to fill an NIH-funded postdoctoral position to study the structure, function, and pharmacology of ion channel complexes. We probe the molecular underpinnings of fast synaptic transmission using various cutting-edge, multidisciplinary approaches, including cryo-EM, Cryo-ET, electrophysiology, and other biophysical methods. Case Western Reserve University has an outstanding infrastructure for structural biology research, including the Titan Krios 3Gi, Glacios, and Aquilos-2 microscopes.

Qualifications

PhD Degree (or expected soon) in physiology, structural biology, biochemistry, pharmacology, or closely related discipline with 0-4 years of postdoctoral experience. Prior experience in patch-clamp electrophysiology, membrane protein biochemistry, cellular neuroscience, and Cryo-EM is preferred. Excellent oral and written communication are essential. Strong project management and scientific writing skills are expected.

In compliance with the City of Cleveland’s Pay Transparency Ordinance (effective October 27, 2025), the annual starting base salary range for this position is $55,000 - $63,480. CWRU considers factors such as (but not limited to) the specific grant funding and the terms of the research grant when extending an offer. Postdocs receive individual and family healthcare benefits, life insurance, and employee assistance.

Case Western Reserve University is an equal opportunity employer. All applicants are protected under federal and state laws and university policy from discrimination based on race, color, religion, sex, sexual orientation, gender identity or expression, national or ethnic origin, protected veteran status, disability, age and genetic information.

Reasonable Accommodation Statement:
Case Western Reserve University complies with the Americans with Disabilities Act regarding reasonable accommodations for applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity by phone at 216.368.3066 or by email at [e-mail] . Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.