Postdoc: Cancer Multi-Omics Bioinformatics & Biostatistics

Baylor College of Medicine; Houston (TX); On-site; USD 57,000 - 70,000; Full time

Job summary

Baylor College of Medicine in Houston, TX, seeks a Postdoctoral Associate in Cancer Bioinformatics, Biostatistics, and Multi-Omics. Onsite work with strong R/Python skills and experience in multi-omics data analysis.

The role includes computational workflow development, data integration, and biomarker discovery in translational cancer research. The candidate will analyze bulk and single-cell omics, spatial data, and imaging modalities, using HPC resources and reproducible pipelines.

Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• Ph.D. in Bioinformatics, Computational Biology, Biostatistics, Statistics, Biomedical Informatics, Data Science, cancer biology, Genomics, Systems Biology, or related quantitative field.

Responsibilities

• Develops, implements, and maintains reproducible bioinformatics pipelines for large-scale cancer omics datasets.
• Analyzes bulk RNA-seq data, including QC, normalization, differential expression, and GSEA.
• Analyzes single-cell RNA-seq datasets including QC, clustering, cell-type annotation, and trajectory analysis.
• Performs computational analysis of spatial transcriptomics data and integrates with single-cell datasets.
• Analyzes proteomics/metabolomics datasets and integrates with transcriptomic data.
• Analyzes ATAC-seq and ChIP-seq data, including QC, peak identification, motif analysis, and TF activity.
• Analyzes imaging mass cytometry/CyTOF data for high-dimensional phenotyping and spatial analysis.
• Develops multi-omics integration methods and biomarker discovery workflows.
• Develops and applies ML/statistical models for biomarker discovery and patient stratification.
• Establishes standardized workflows, version control, and documentation.

Skills

R programming

Python programming

Biostatistics

Bioinformatics

Machine learning

Single-cell analysis

Education

MD or PhD in Basic/Health Sciences

PhD in Bioinformatics/Computational Biology/Statistics/Data Science

Tools

Linux/Unix

GraphPad Prism

Job description

Baylor College of Medicine in Houston, TX, seeks a Postdoctoral Associate in Cancer Bioinformatics, Biostatistics, and Multi-Omics. Onsite work with strong R/Python skills and experience in multi-omics data analysis.

The role includes computational workflow development, data integration, and biomarker discovery in translational cancer research. The candidate will analyze bulk and single-cell omics, spatial data, and imaging modalities, using HPC resources and reproducible pipelines.