Post Doctoral Scholar-Comprehensive Cancer Center

Ohio State University; Columbus (OH); On-site; USD 50,000 - 65,000; Full time

Job summary

The Ohio State University Wexner Medical Center in Columbus, OH seeks a Postdoctoral Scholar to conduct independent and collaborative cancer immunology research within the PIIO. The role focuses on understanding mechanisms of response and resistance to cancer immunotherapy using patient-derived samples and preclinical models.

Applicants should have a PhD/MD-PhD and strong experience in cellular/molecular biology, flow cytometry, and data interpretation.

Qualifications

• PhD, MD/PhD, or equivalent doctoral degree in Immunology, Cancer Biology, Molecular Biology, Cell Biology, Biomedical Sciences, Oncology, or related field.
• Experience conducting independent scientific research in cancer biology, immunology, translational medicine, or related discipline.
• Demonstrated expertise in cellular and molecular biology techniques.
• Experience with flow cytometry, immune profiling, molecular analyses, and experimental design.
• Strong analytical, scientific writing, communication, and data interpretation skills.
• Ability to work effectively in multidisciplinary and collaborative research environments.

Responsibilities

• Conduct independent and collaborative research in cancer immunology within the PIIO lab.
• Design and execute mechanistic studies using patient-derived samples and preclinical models.
• Utilize advanced immune profiling technologies and molecular biology approaches.
• Develop biomarkers and immunotherapeutic strategies for cancer treatment.
• Prepare manuscripts and present findings at scientific conferences.

Skills

Immunology

Molecular biology

Flow cytometry

Data analysis

Scientific writing

Collaborative research

Education

PhD/MD-PhD or equivalent

Tools

Multiparameter flow cytometry

qPCR

Immunoblotting

ELISA

Spatial biology imaging

Job description

The Postdoctoral Scholar will conduct independent and collaborative research within the laboratory of Dr. Hassane Zarour at the OSUCCC – James Pelotonia Institute for Immuno-Oncology (PIIO). The position will focus on basic and translational cancer immunology research aimed at understanding mechanisms of response and resistance to cancer immunotherapy, immune checkpoint blockade, and tumor microenvironment-mediated immune dysfunction. The Postdoctoral Scholar will design and execute mechanistic studies utilizing patient-derived samples, advanced immune profiling technologies, molecular biology approaches, and preclinical models to advance novel immunotherapeutic strategies and biomarkers for cancer treatment. **Required Qualifications*** PhD, MD/PhD, or equivalent doctoral degree in Immunology, Cancer Biology, Molecular Biology, Cell Biology, Biomedical Sciences, Oncology, or a related biomedical science field.* Experience conducting independent scientific research in cancer biology, immunology, translational medicine, or a related discipline.* Demonstrated expertise in cellular and molecular biology techniques.* Experience with flow cytometry, immune profiling, molecular analyses, and experimental design.* Strong analytical, scientific writing, communication, and data interpretation skills.* Ability to work effectively in multidisciplinary and collaborative research environments.**Preferred Qualifications*** Experience in cancer immunology, tumor immunology, immune checkpoint biology, or immunotherapy research.* Experience with multiparameter flow cytometry, tumor-infiltrating lymphocyte analyses, and immune monitoring technologies.* Experience with multiplex immunohistochemistry, spatial biology, tissue imaging, and quantitative image analysis platforms.* Experience with animal models of cancer, including tumor implantation, tissue collection, and surgical procedures.* Experience with molecular biology techniques including cell culture, PCR, immunoblotting, ELISA, viral vector systems, and genetic manipulation approaches.* Record of peer-reviewed publications and scientific presentations.* Experience mentoring students, trainees, or laboratory personnel.## Additional Information:The OSUCCC – James is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nation's largest public universities. The OSUCCC – James Pelotonia Institute for Immuno-Oncology (PIIO) is a comprehensive bench-to-bedside research initiative focused on harnessing the body's immune system to fight cancer at all levels, from prevention to treatment and survivorship. Trainees benefit from an enriching educational environment led by world-renowned mentors in cancer immunotherapy, complemented by a robust seminar series, access to top-tier research facilities, and a dynamic culture of innovation that drives transformative discoveries in cancer care.## Location:Biomedical Research Tower (0112)## Position Type:Term (Fixed Term)## Scheduled Hours:40## **Shift:**First Shift