Post Doctoral Fellow - Rockefeller Neuroscience Institute Department of Neuroscience

West Virginia University; Morgantown (WV); On-site; USD 10,000 - 60,000; Full time

Job summary

An established industry player is seeking a highly motivated Postdoctoral Fellow to explore the molecular biology of synapses at the Rockefeller Neuroscience Institute. This role involves utilizing advanced imaging techniques, particularly STED super-resolution microscopy, to investigate synaptic structures and their role in neurodegenerative diseases. The successful candidate will lead innovative research aimed at understanding synaptic plasticity and its implications for brain health. Join a dynamic team dedicated to groundbreaking research in neuroscience, where your contributions will have a profound impact on understanding and treating neurodegenerative conditions.

Benefits

403(b) retirement savings with matching contributions

Comprehensive benefits package

Work-life balance initiatives

Qualifications

• Ph.D. in neuroscience or related field required.
• Expertise in synaptic biology and imaging techniques is essential.

Responsibilities

• Conduct molecular and imaging analyses of synaptic organization.
• Design and execute experiments on synaptic remodeling and plasticity.

Skills

Synaptic Biology

Super-Resolution Microscopy

Neurodegenerative Disease Models

Cell Culture Preparation

Data Analytics

DNA Manipulation/Cloning

CRISPR Technology

Independent Thinking

PCR

Western Blotting

Education

Ph.D. in Neuroscience

Ph.D. in Molecular Biology

Ph.D. in Biochemistry

Tools

STED Microscopy

Confocal Microscopy

Java

Python

Job description

Job Description - Post Doctoral Fellow - Rockefeller Neuroscience Institute Department of Neuroscience (25883)

The Department of Neuroscience at West Virginia University Research Corporation is currently accepting applications for a Post Doctoral Fellow in Synaptic Molecular Biology and Super-Resolution Imaging at the Rockefeller Neuroscience Institute.

About the Opportunity

The laboratory of Martin Hruska, Ph.D., is seeking a highly motivated and creative Postdoctoral Associate to investigate the molecular biology of synapses using advanced imaging techniques, including STED super-resolution microscopy. Our research explores the fundamental mechanisms of synapse formation, plasticity, and remodeling, with a focus on how these processes are disrupted in neurodegenerative diseases such as Alzheimer’s disease.

The successful candidate will lead a project examining the structural and molecular underpinnings of synaptic remodeling that drive brain plasticity in health and neurodegeneration. This work leverages molecular biology, biochemistry, and cutting-edge imaging methods to uncover how nanoscale synaptic architecture regulates neuronal function.

At WVU Research Corporation, we strongly believe in work-life balance and keeping time for things we love outside our work. WVU Research Corporation offers a comprehensive benefits package with a variety of options to suit your needs:

• 403(b) retirement savings with a fully vested 3% employee contribution match, (Employees have the option of contributing an additional 1-3% of their earnings to the plan, which is also matched by the WVURC)

Responsibilities

• Perform molecular and imaging analyses to investigate nanoscale synaptic organization.
• Use STED microscopy to resolve synaptic components in cultured neurons and brain sections.
• Design and conduct experiments on synaptic remodeling and plasticity.
• Maintain high standards of laboratory organization and academic integrity.
• Conduct literature reviews, analyze data, and prepare manuscripts.
• Present findings at national and international conferences.

Qualifications

• Ph.D. in neuroscience, molecular biology, biochemistry, or a related field.
• Experience in the following:
• Expertise in synaptic biology, plasticity, and/or neurodegenerative disease models.
• Hands-on experience with super-resolution microscopy techniques (preferably STED) and imaging of neuronal cultures or brain tissue.
• Proficiency in cell culture preparation, protein quantification, confocal microscopy, and data analytics.
• Coding skills (e.g., Java, Python) are a plus.
• All qualifications must be met by the time of employment.

Knowledge, Skills and Abilities

• DNA manipulation/cloning
• CRISPR technology
• Cell culture preparation
• PCR, Western blotting, and protein assays
• Independent thinking

Requirements

• Biohazards training certificate (CITI) Human subjects training certificate (CITI)
• Conflict of interest in research certificate (CITI)
• These are federal regulations; the candidate can complete them after beginning the position if s/he is not already certified before being hired.

About Research Corporation

The WVURC was created as a not-for-profit corporation in 1985 to support research (R1) at West Virginia University. We provide evaluation, development, patenting, management, and marketing services for inventions of the faculty, staff and students of the University.

The WVURC receives and administers funds awarded by external agencies for research and other activities and is responsible for helping protect intellectual property through patents, copyrights and licensing agreements for start-up companies based on University research.

West Virginia University Research Corporation is proud to be an Equal Opportunity employer. We value diversity among its employees and invite applications from all qualified applicants regardless of race, ethnicity, color, religion, gender identity, sexual orientation, age, nationality, genetics, disability, or Veteran status.

Job Posting

Job Posting: Jan 10, 2025

Posting Classification: Research Corporation