Post-Doctoral Fellow - Myosin Phosphatase

University of Maryland, Baltimore; Baltimore (MD); On-site; USD 50,000 - 70,000; Full time

Job summary

A full-time Post-Doctoral fellowship position is available in the Division of Cardiology at the University of Maryland-Baltimore. The role focuses on vascular smooth muscle gene expression and contractility in blood flow regulation, with a novel therapy approach for hypertension and heart failure.

Qualifications

• Expertise in techniques of cell and molecular biology required.
• Familiarity with experimental techniques for studying small blood vessels preferred.

Responsibilities

• Perform experiments in animal models using Cre-Lox and AAV-Crispr/Cas9 editing.
• Test hypothesis on myosin phosphatase's role in blood pressure regulation.

Skills

Cell Biology

Molecular Biology

Education

Ph.D.

M.D.

Job description

Job Description

Post-doctoral research position in Division of Cardiology University of Maryland

A full time Post-Doctoral fellowship position is available in the laboratory of Dr. Steven Fisher in the Division of Cardiology at the University of Maryland-Baltimore as of October 1, 2020. The federally funded project examines vascular smooth muscle gene expression and contractility in the regulation of blood flow in development and disease models. The focus is on the myosin phosphatase (MP), a critical target of signals that regulate blood flow. Experiments will test the hypothesis that editing of MP lowers blood pressure in models of hypertension and heart failure, and will determine the mechanism(s) by which it does so. The post-doc will perform experiments in animal models using Cre-Lox and AAV-Crispr/Cas9 editing of MP in vivo. The AAV-Crispr/Cas9 approach of editing is in pre-clinical development as a novel therapy for humans with hypertension and heart failure. Applicants are required to have a Ph.D. or M.D. and expertise in techniques of cell and molecular biology. Familiarity with experimental techniques required for the study of small blood vessels is preferred but not required.

If interested please email a CV, a short statement of research interests, and the names and contact information for three

references to:

Steven Fisher, MD, Professor of Medicine and Physiology, at
[e-mail]



Qualifications

Applicants are required to have a Ph.D. or M.D. and expertise in techniques of cell and molecular biology. Familiarity with experimental techniques required for the study of small blood vessels is preferred but not required.

University of Maryland is an Equal Opportunity Employer encouraging excellence through diversity. Qualified woman and minority candidates are encouraged to apply.