Pharmacometrics Strategy Lead | PK/PD & Modeling

AbbVie Inc.; North Chicago (IL); Sur place; USD 150 000 - 210 000; Plein temps

Résumé du poste

AbbVie in the United States is seeking an Associate Director, Pharmacometrics to lead PMx strategy and deliver analyses across drug development programs. The role provides expert consultancy, shapes PMx methodologies, and partners with CPPM and project teams to drive regulatory-ready deliverables.

The successful candidate will have a PhD or equivalent with extensive PK/PD modeling, strategic leadership, and strong communication to influence cross-functional stakeholders and advance therapeutic

Qualifications

• PhD with 5+ years (or Master with 11+ years) in pharmacometrics or related field.
• Strategic thinker with enterprise view and cross-functional influence.
• Proven track record in PMx modeling, simulation, or PK/PD analyses.
• Strong project management and leadership capabilities.

Responsabilités

• Drive PMx strategy across multiple projects and programs; collaborate with CPPM leadership.
• Ensure quality and accuracy of pharmacometrics deliverables.
• Advise on advanced analytics, ML, and mechanistic modeling?
• Ensure timely PMx regulatory documents and responses to agency comments.
• Represent Pharmacometrics in core team meetings and drive process improvements.

Connaissances

Pharmacometric modeling

PK/PD analysis

Strategic leadership

Cross-functional collaboration

Regulatory science

Formation

PhD in pharmacometrics or related field

MS in statistics/pharmacometrics

Outils

NONMEM

R

Python

Description du poste

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

Job Description

The Associate Director, Pharmacometrics will act as an internally and externally recognized pharmacometrician by driving pharmacometrics (PMx) strategy, performing PMx analyses and representing PMx in project teams. They will continuously and consistently develop, implement, and promote innovative PMx methodologies/approaches and provide consultancy and expert advice to other stakeholders. Develop PMx strategy for projects and indications.

Responsibilities

• Drive Pharmacometrics PK/PD strategy across multiple major projects and programs; collaborate with CPPM senior management in the selection of action plans that best meets business needs in drug development
• Responsible for the appropriateness, quality and accuracy of pharmacometrics deliverables
• Advise on complex methodologies such as advanced analytics, machine learning and mechanistic modeling
• Ensure the timely delivery of PMx regulatory documents and response to regulatory agency comments
• Contribute to development of departmental goals; influences strategic PK/PD decisions for the department
• Maintain up-to-date knowledge of industry standards in PK/PD data analyses, modeling and simulation methods and software
• Represent Pharmacometrics in core team meetings
• Champion development, implementation, and promotion of innovative PMx approaches across therapeutic areas; identify and develop process improvement initiatives
• Participate in internal and external initiatives/working groups (e.g., cross-functional initiatives, process harmonization, IMI calls, ISoP groups)
• May manage personnel including their development, mentoring, and effective delegation

Qualifications

• PhD with 5+ year of experience or Master’s degree with 11+ years of experience in a relevant field such as (bio-)statistical modeling and simulation, PKPD modeling, system pharmacology
• Strategic thinking and enterprise view
• Proven scientific track record and technical skills to perform the role
• Demonstrated project management skills such as scope management and progress tracking/driving
• Key Leadership Competencies: Understand the business and the cross-functional contributions needed to deliver results; Develops strategic perspective; Connects unrelated concepts, generates original or unique ideas; Influences colleagues to achieve cross-functional alignment; Communicates openly and honestly with all colleagues; Manages conflict and difficult conversations in a constructive and transparent way; Inspires and motivates others and self to high performance

Additional Information

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html