Pharmacometric Leader: PK/PD Modeling & Strategy

AbbVie Inc.; North Chicago (IL); On-site; USD 140,000 - 210,000; Full time

Job summary

AbbVie is seeking a senior Pharmacometrician to conceive, execute, and communicate multi-disciplinary PK/PD modeling and simulations to support development plans and regulatory requirements across functions.

You will generate new modeling proposals, lead efforts, and critically evaluate technical aspects with Clinical Pharmacology and Pharmacometrics leadership while collaborating on multiple projects and external interactions.

Qualifications

• PhD with typically 3+ years of experience in a relevant field
• Master's Degree or equivalent education and typically 9+ years of experience
• Bachelor's Degree or equivalent education and typically 13+ years of experience

Responsibilities

• Execute strategy and lead data analyses and interpretation with MoA and disease specifics
• Assist senior management in selecting action plans for drug development
• Author regulatory PK/PD analysis plans, study reports, exposure-response analyses and regulatory documents
• Represent Pharmacometrics in clinical projects and present to leadership
• Collaborate to develop a unified Clinical Pharmacology position
• Publish scientific work and present at conferences
• Participate in internal and external initiatives and working groups

Skills

Pharmacometric modeling

Interdisciplinary collaboration

Strategic thinking

Leadership in cross-functional teams

Education

PhD in Pharm/biostatistics/data science

Master's degree or equivalent

Bachelor's degree or equivalent

Job description

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

Job Description

Conceive, execute and communicate multi-disciplinary modeling and simulations exercises to support development plans and strategies to achieve commercial goals and regulatory requirements for multiple functions. Generate new PK/PD modeling and simulation proposals and leads those efforts. Investigate, identify, develop, and optimize new methods and techniques in the field of PK/PD modeling and statistical data analysis. Consistently demonstrates excellent record of accomplishment of Pharmacometric and business objectives. Leads Pharmacometric and PK/PD modeling aspects of multiple projects. Responsible for critically evaluating technical and scientific aspects along with Clinical Pharmacology and Pharmacometrics management.

Responsibilities

• Execute strategy, lead teams and various data analyses and interpretation by providing necessary context (including explaining MoA and disease specifics, available relevant internal and external data, analysis plans, interpretation and discussion of model results in the context of research question).
• Assist Clinical Pharmacology senior management in the selection of action plans that best meet business needs in drug development.
• Author regulatory documents including PK/PD analysis plans, study reports, population PK reports, exposure-response analyses reports, common technical documents, label, white papers, and other similar documents.
• Represent Pharmacometrics in Clinical Pharmacology and clinical project teams and presents in project team meetings and to Clinical Pharmacology Leadership.
• Collaborate with the Clinical Pharmacology TA leads to develop a unified Clinical Pharmacology position.
• Authors scientific publications and present at national and international conferences and interact with external stakeholders.
• Participate in internal and external initiatives/working groups (e.g., process harmonization, IMI calls, ISoP groups).

Qualifications

• PhD with typically 3+ years of experience in a relevant field, Master’s Degree or equivalent education and typically 9+ years of experience, Bachelor’s Degree or equivalent education and typically 13+ years of experience;(*relevant field includes experience with data science, mathematics, biostatistics, modeling and simulation, Pharmacometrics or systems pharmacology)
• Excellent interpersonal skills
• Ability to interact with functional representatives internally
• Strategic thinking and enterprise view
• Proven scientific track record and technical skills to perform the role
• Key Leadership Competencies:
  o Delivers business results while also positioning AbbVie for long-term success
  o Persistent and resilient finds the way to move good ideas forward
  o Acts respectfully yet courageously
  o Connects unrelated concepts, generates original or unique ideas
  o Influences colleagues to achieve cross-functional alignment
  o Gives full accountability when delegating and accepts full accountability when delegated to by others

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible toparticipatein our long-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paid andmay bemodifiedat the Company’s sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html