Pharma Reliability Engineer: Uptime & Lean Improvement

AstraZeneca plc; Philadelphia (Philadelphia County); Hybrid; USD 110,000 - 150,000; Full time

Job summary

AstraZeneca plc is seeking a Reliability Engineer at our Philadelphia site to connect long-term asset strategies with real-time production support. You will drive uptime, quality, and speed through RCA, Lean methods, and risk-based lifecycle management in a cGMP environment.

Partner with Facilities, Engineering, and Manufacturing to build data-driven reliability programs, lead cross-functional teams, and deliver projects on time and within budget.

Qualifications

• 3+ to 5+ years of Reliability Engineering experience in pharma/biotechnology, nuclear, or petrochemical industries.
• High school diploma.
• Experience leading and working on cross-functional teams supporting technical projects.

Responsibilities

• Maintain monthly maintenance performance reviews with Facilities and Engineering to improve uptime and compliance.
• Define and track KPIs to improve equipment availability and MTBF.
• Investigate equipment failures using RCA tools and implement corrective actions.
• Lead end-to-end projects with scope, planning, resources, risk management, and stakeholder alignment.
• Apply risk-based lifecycle management to critical systems to extend asset life.
• Plan and implement preventive and predictive maintenance programs to reduce downtime.
• Coordinate validation activities to ensure project quality and compliance.
• Collaborate with Manufacturing and site partners to align priorities and drive outcomes.

Skills

Reliability engineering

Root cause analysis

Lean / Six Sigma

Cross-functional collaboration

Project leadership

Education

Bachelor's degree in Engineering or related field

High school diploma

Tools

Thermography cameras

Vibration analysis equipment

Ultrasonic testing equipment

Job description

AstraZeneca plc is seeking a Reliability Engineer at our Philadelphia site to connect long-term asset strategies with real-time production support. You will drive uptime, quality, and speed through RCA, Lean methods, and risk-based lifecycle management in a cGMP environment.

Partner with Facilities, Engineering, and Manufacturing to build data-driven reliability programs, lead cross-functional teams, and deliver projects on time and within budget.