Organic Lipid Chemist – Process Development & Scale-Up

Integrated Resources, Inc ( IRI )

Rockford (IL)

On-site

USD 90,000 - 120,000

Full time

3 days ago
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Job summary

Integrated Resources, Inc ( IRI ) is seeking an Organic Chemist/Scientist to develop, optimize, and document fatty-acid-related synthesis and purification processes for raw materials used in cell-culture media production.

The role focuses on fatty acids and lipids with potential expansion to other materials. You will perform multi-step syntheses, characterize products with HPLC/LC-MS/NMR, troubleshoot issues, and support transfer of processes to Rockford manufacturing operations.

Qualifications

  • MS/PhD in Organic Chemistry or closely related field.
  • Industrial experience in organic synthesis and process development is valued.
  • Ability to design, optimize, and document multi-step syntheses for lipid-related materials.

Responsibilities

  • Design and execute lab experiments for synthesis and process development of fatty acids, glycerides, phospholipids, and related lipids.
  • Develop and optimize synthetic routes with emphasis on yield, purity, reproducibility, and scalability.
  • Develop purification strategies using chromatography, HPLC, crystallization, extraction, and related methods.
  • Characterize materials using HPLC, LC-MS/MS, NMR, FT-IR, UV/Vis, and related techniques.
  • Troubleshoot reactions and purification processes to meet specifications.
  • Perform feasibility studies with alternate starting materials and define conditions for quality targets.
  • Support scale-up from lab to gram/hundreds of gram scales and transfer to manufacturing.
  • Collaborate with Analytical Development to ensure fit-for-purpose methods.
  • Prepare materials for internal evaluation, packaging, process validation, and transfer.
  • Write protocols, reports, batch instructions, and technical summaries with traceability.
  • Maintain accurate lab records and data integrity for assessments and decisions.
  • Work cross-functionally with R&D, Analytical, Operations, Quality, Procurement, and PM teams.

Skills

Organic synthesis
Reaction optimization
Multi-step synthesis
Purification techniques
Analytical data interpretation
Documentation
Cross-functional collaboration
Communication skills

Education

M.S./Ph.D. in Organic Chemistry
Bachelor’s degree with relevant experience

Tools

HPLC
LC-MS/MS
NMR
FT-IR

Job description

Integrated Resources, Inc ( IRI ) is seeking an Organic Chemist/Scientist to develop, optimize, and document fatty-acid-related synthesis and purification processes for raw materials used in cell-culture media production.

The role focuses on fatty acids and lipids with potential expansion to other materials. You will perform multi-step syntheses, characterize products with HPLC/LC-MS/NMR, troubleshoot issues, and support transfer of processes to Rockford manufacturing operations.

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