Operator - Isotope Production

Biopharma Careers; Indianapolis (IN); On-site; USD 43,000 - 51,000; Full time

Benefits offered by this job

Health Coverage

Wellbeing Programs

401(k) plan

Paid Time Off

Job summary

RayzeBio, an oncology-focused radiopharmaceutical company, seeks an Operator – Isotope Production to join the GMP-driven manufacturing team in Indianapolis. You’ll help produce clinical and commercial isotopes, uphold safety standards, and ensure compliant operations on the production floor.

Ideal candidates have GMP experience, STEM degrees, and strong English communication skills to collaborate across Quality, Radiochemistry, and Engineering groups while delivering reliable isotope products.

Qualifications

• 1–4 years' experience in a GMP environment.
• Associate’s or Bachelor’s Degree in a STEM field preferred.
• Fluency in English.
• Strong knowledge of GMP practices.
• Pipetting knowledge and experience.
• Knowledge of radiation safety principles.
• Knowledge of radiopharmaceutical manufacturing.
• Excellent professional ethics, integrity, and ability to maintain confidential information.
• Well organized and detail oriented.
• Strong interpersonal communication skills.
• Motivated, adaptable, and able to work under pressure while meeting production schedule.

Responsibilities

• Execute routine isotope production (material prep, equipment setup, batch execution, waste disposal) with GMP and NRC compliance.
• Perform radiochemical separations using hot cell equipment and glove box isolator per batch records.
• Collaborate with cross‑functional teams to optimize production processes and efficiency.
• Support investigation of quality events and implement corrective actions.
• Assist inventory management of consumables, spare parts, cleaning supplies and PPE.
• Promote safety and compliance with EHS and Radiation Safety programs.

Skills

English fluency

GMP knowledge

Pipetting

Radiation safety

Radiopharmaceuticals

Ethics & confidentiality

Organized

Interpersonal skills

Stress tolerance

AI tools usage

Education

Associate's or Bachelor's Degree in STEM

Tools

Glove box handling

Hot cells

Job description

At RayzeBio, every day is an opportunity to ignite meaningful change. As a wholly‑owned subsidiary of Bristol Myers Squibb, RayzeBio blends the nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer. Here, you’ll join a multidisciplinary team where your ideas are valued, your expertise is amplified, and collaboration is at the heart of everything we do. From day one, expect to make an immediate impact, on our science, on our teams, and most importantly, on patients. Learn more about RayzeBio: https://careers.bms.com/rayzebio/

Summary

The Operator – Isotope Production will be an integral part of bringing RayzeBio’s innovative drug products to patients in need. As Operator within the Isotope Production department, you will be instrumental in the day‑to‑day execution of an isotope production program that will manufacture the clinical and commercial scale radioisotopes for RayzeBio’s drug products. This individual will be part of a team responsible for producing RayzeBio’s isotopes under Good Manufacturing Practices (GMP). Additionally, you will be the front line in ensuring compliance with radiation safety requirements on the production floor. This position will report to the Supervisor – Isotope Production. Operator level will be evaluated with experience and qualifications.

Job Responsibilities

• Execute routine isotope production (including material preparation, equipment setup, batch execution, post‑batch material removal, waste disposal etc.) while ensuring compliance with GMP, site SOPs, NRC regulations, and management expectations.
• Perform radiochemical separations utilizing hot cell equipment and isotope purification within a glove box isolator in accordance with applicable batch records.
• Work with cross‑functional teams including Management, Quality, Radiochemistry, and Engineering identifying opportunities to optimize production processes and enhance efficiency.
• Support the investigation of quality events, including the implementation of corrective actions.
• Support inventory management, including consumables, spare parts, cleaning supplies and personal protective equipment (PPE).
• Promote and model a culture of safety and compliance with EHS and Radiation Safety programs.

Education and Experience

• Previous experience operating within hot cells and/or glove boxes is strongly preferred.
• 1 – 4 years’ experience operating in a GMP environment.
• Associate’s or Bachelor’s Degree in a STEM field is preferred.

Skills and Qualification

• Fluency in English.
• Strong knowledge of GMP practices.
• Pipetting knowledge and experience.
• Knowledge of radiation safety principles.
• Knowledge of radiopharmaceutical manufacturing.
• Excellent professional ethics, integrity, and ability to maintain confidential information.
• Well organized and detail oriented.
• Strong interpersonal communication skills.
• Motivated, adaptable, and able to work under pressure while meeting the needs of the production schedule.
• Uses AI tools to enhance individual productivity and quality of work

Physical Demands

While performing the duties of this job, the employee is regularly required to sit, reach with hands and arms, and talk or hear. The employee must occasionally lift and/or move up to 50 pounds. Specific vision abilities required by this job include close vision and distance vision. Must be willing to wear personal protective equipment (PPE) for long periods. This is a position that requires working in a laboratory environment, protective clothing, gloves, and safety glasses are required while working in a laboratory environment with radioactive materials.

Work Environment

The noise level in the work environment is usually moderate.

Compensation Overview

Indianapolis - RayzeBio - IN: $31.07 - $37.64per hour

The starting compensation range(s) for this role are listed above for a full‑time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job‑related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.

Benefit Offerings

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well‑Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well‑being and Protection: 401(k) plan, short‑and‑long‑term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work‑life benefits include:

• Paid Time Off
• US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non‑Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
• Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
• All global employees full and part‑time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

*Eligibility Disclosure

T he summer hours program is for United States (U.S.) office‑based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote‑by‑design or lab‑based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

RayzeBio and Bristol Myers Squibb

RayzeBio was acquired by Bristol Myers Squibb (BMS) in 2024 and is a wholly‑owned subsidiary of BMS; however, RayzeBio will continue to operate as a standalone organization.

Supporting People with Disabilities

BMS and RayzeBio are dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS and RayzeBio will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection/. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

R1602816: Operator - Isotope Production