Operator - Isotope Production

Bristol-Myers Squibb Company; Guam; On-site; USD 43,000 - 52,000; Full time

Benefits offered by this job

Flexible Time Off

11 paid holidays

Vacation time (160 hours)

Job summary

RayzeBio in Indianapolis, IN, is seeking an Operator – Isotope Production to execute routine isotope production and ensure GMP compliance. You will conduct radiochemical separations in hot cells and glove boxes, while collaborating with Quality, Radiochemistry, and Engineering teams to optimize processes.

The role requires 1–4 years in GMP environments, experience with hot cells/glove boxes, and a STEM degree.

Qualifications

• 1–4 years’ experience operating in a GMP environment.
• Previous experience operating within hot cells and/or glove boxes.
• Associate’s or Bachelor’s Degree in a STEM field is preferred.

Responsibilities

• Execute routine isotope production (material prep, equipment setup, batch execution, post-batch removal, waste disposal) with GMP compliance.
• Perform radiochemical separations using hot cell equipment and glove box isolator per batch records.
• Collaborate with cross-functional teams (Management, Quality, Radiochemistry, Engineering) to optimize production and efficiency.
• Support investigation of quality events and implement corrective actions.
• Assist in inventory management of consumables, parts, cleaning supplies, and PPE.
• Promote safety and compliance with EHS and Radiation Safety programs.

Skills

Fluency in English

GMP practices

Pipetting

Radiation safety

Radiopharmaceuticals

Ethics & confidentiality

Detail oriented

Interpersonal skills

Work under pressure

AI productivity tools

Education

STEM degree

Tools

Hot cell equipment

Glove box isolator

Job description

Life at BMS

At RayzeBio, every day is an opportunity to ignite meaningful change. As a wholly-owned subsidiary of Bristol Myers Squibb, RayzeBio blends the nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer. Here, you’ll join a multidisciplinary team where your ideas are valued, your expertise is amplified, and collaboration is at the heart of everything we do. From day one, expect to make an immediate impact—on our science, on our teams, and most importantly, on patients. Learn more about RayzeBio: https://careers.bms.com/rayzebio/

The Operator – Isotope Production

The Operator – Isotope Production will be an integral part of bringing RayzeBio’s innovative drug products to patients in need. As Operator within the Isotope Production department, you will be instrumental in the day-to-day execution of an isotope production program that will manufacture the clinical and commercial scale radioisotopes for RayzeBio’s drug products. This individual will be part of a team responsible for producing RayzeBio’s isotopes under Good Manufacturing Practices (GMP). Additionally, you will be the front line in ensuring compliance with radiation safety requirements on the production floor.

This position will report to the Supervisor – Isotope Production. Operator level will be evaluated with experience and qualifications.

Job Responsibilities

• Execute routine isotope production (including material preparation, equipment setup, batch execution, post-batch material removal, waste disposal etc.) while ensuring compliance with GMP, site SOPs, NRC regulations, and management expectations.
• Perform radiochemical separations utilizing hot cell equipment and isotope purification within a glove box isolator in accordance with applicable batch records.
• Work with cross-functional teams including Management, Quality, Radiochemistry, and Engineering identifying opportunities to optimize production processes and enhance efficiency.
• Support the investigation of quality events, including the implementation of corrective actions.
• Support inventory management, including consumables, spare parts, cleaning supplies and personal protective equipment (PPE).
• Promote and model a culture of safety and compliance with EHS and Radiation Safety programs.

Education and Experience:

• Previous experience operating within hot cells and/or glove boxes is strongly preferred.
• 1 – 4 years’ experience operating in a GMP environment.
• Associate’s or Bachelor’s Degree in a STEM field is preferred.

Skills and Qualification:

• Fluency in English.
• Strong knowledge of GMP practices.
• Pipetting knowledge and experience.
• Knowledge of radiation safety principles.
• Knowledge of radiopharmaceutical manufacturing.
• Excellent professional ethics, integrity, and ability to maintain confidential information.
• Well organized and detail oriented.
• Strong interpersonal communication skills.
• Motivated, adaptable, and able to work under pressure while meeting the needs of the production schedule.
• Uses AI tools to enhance individual productivity and quality of work

Physical Demands:

While performing the duties of this job, the employee is regularly required to sit, reach with hands and arms, and talk or hear. The employee must occasionally lift and/or move up to 50 pounds. Specific vision abilities required by this job include close vision and distance vision. Must be willing to wear personal protective equipment (PPE) for long periods. This is a position that requires working in a laboratory environment, protective clothing, gloves, and safety glasses are required while working in a laboratory environment with radioactive materials.

Work Environment:

The noise level in the work environment is usually moderate.

Compensation Overview:

Indianapolis - RayzeBio - IN: $31.07 - $37.64per hour

The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits:

• Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).
• U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.
• Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.
• Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.
• U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits

RayzeBio and Bristol Myers Squibb

RayzeBio was acquired by Bristol Myers Squibb (BMS) in 2024 and is a wholly-owned subsidiary of BMS; however, RayzeBio will continue to operate as a standalone organization.

Supporting People with Disabilities

BMS and RayzeBio are dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail] . Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS and RayzeBio will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

For roles based in Washington State only: If you live in or expect to work from Washington State if hired for this position, please visit this page for important information about the Washington Fair Chance Act.

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection .

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] with the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1607926 : Operator - Isotope Production