Oncology Site Activation Lead

Worldwide Clinical Trials; Durham (NC); On-site; USD 86,000 - 170,000; Full time

Job summary

Worldwide Clinical Trials is seeking a Site Activation Manager in the United States to lead start‑up activities for Oncology studies, coordinating cross‑functional teams and ensuring milestones are met on time and within budget.

The role requires a four‑year degree (or nursing degree) and at least 4 years CRO start‑up experience, with strong regulatory knowledge and excellent English communication. This position offers growth within a global CRO and a collaborative, inclusive culture.

Qualifications

• A minimum four-year degree or nursing degree is required.
• Minimum of 4 years CRO experience in Study Start-Up with country lead or manager experience.
• Proficient in cross-cultural communication.
• Proficient in both spoken and written English.

Responsibilities

• Serve as the primary point of accountability for site activation and start‑up activities on assigned studies.
• Oversee cross‑functional site activation activities to ensure milestones are achieved on time and within budget.
• Manage the accurate tracking, analysis, and reporting of site activation progress and metrics.
• Partner with project teams to support feasibility, site qualification, selection, and regulatory activities as needed.
• Communicate site activation status, risks, and mitigation plans to Sponsors, project leadership, and internal teams.
• Develop and maintain site activation project plans and support risk assessment and issue resolution.
• Ensure site activation activities are appropriately budgeted, with out‑of‑scope work tracked and managed through change control.
• Drive continuous improvement through SOP development, best practices, metrics, and departmental initiatives.
• Contribute to business development activities, including proposal development and bid defense support.
• Liaise with internal stakeholders and external vendors, escalating issues as needed to ensure on‑time delivery.
• Ensure compliance with SOPs, ICH GCP, and applicable regulatory requirements.

Skills

Leadership

Project management

Regulatory knowledge

Cross-cultural communication

English proficiency

Strategic planning

Team collaboration

MS Office proficiency

Education

4-year degree or nursing degree

Tools

MS Office

Job description

Worldwide Clinical Trials is seeking a Site Activation Manager in the United States to lead start‑up activities for Oncology studies, coordinating cross‑functional teams and ensuring milestones are met on time and within budget.

The role requires a four‑year degree (or nursing degree) and at least 4 years CRO start‑up experience, with strong regulatory knowledge and excellent English communication. This position offers growth within a global CRO and a collaborative, inclusive culture.