Oncology Research Nurse I (PA/NJ Residents ONLY)

St. Luke’s University Health Network; Bethlehem (Northampton County); On-site; USD 85,000 - 110,000; Full time

Job summary

St. Luke’s University Health Network is seeking an Oncology Research Nurse II to coordinate all aspects of care for patients enrolled in clinical trials. The role requires a registered professional nurse with 2+ years of oncology trial experience and preferred clinical research certification (SoCRA/ACRP).

The nurse will maintain regulatory documentation, educate patients on procedures, and communicate findings to staff while supporting trial logistics at multiple sites within the network.

Qualifications

• Registered professional nurse credential required.
• Must have 2+ years direct oncology clinical trials experience.
• Clinical Research certification (SoCRA, ACRP) preferred.

Responsibilities

• Coordinate all aspects of care for patients enrolled in a clinical trial.
• Maintain accurate documentation including regulatory documents and study-related forms.
• Educate patients regarding protocol procedures and treatment regimens.
• Disseminate study information to medical and nursing staff.

Education

Registered professional nurse

Clinical Research certification (SoCRA, ACRP)

Job description

St. Luke's is proud of the skills, experience and compassion of its employees. The employees of St. Luke's are our most valuable asset! Individually and together, our employees are dedicated to satisfying the mission of our organization which is an unwavering commitment to excellence as we care for the sick and injured; educate physicians, nurses and other health care providers; and improve access to care in the communities we serve, regardless of a patient's ability to pay for health care.

The primary responsibility of the Oncology Research Nurse II is to coordinate all aspects of care for the patient enrolled in a clinical trial.

The research nurse is required to have an in-depth knowledge of protocol requirements and good clinical practices as set forth by federal regulations.

JOB DUTIES AND RESPONSIBILITIES

• Sound conduct of the clinical trial, including but not limited to, recruitment, screening, enrollment, and follow-up of eligible subjects according to protocol requirements.
• This includes performing required study procedures as applicable.
• Maintenance of accurate and complete documentation, including but not limited to regulatory documents, signed informed consent forms, source documentation, drug dispensing logs, subjects logs and study-related communication.
• Organizational management of all aspects of the trial including but not limited to timeliness in completing case report forms (CRFs), data entry, reporting adverse drug events, managing caseload and managing study files.
• Communication of all protocol-related issues/problems to the appropriate management staff, and proper communication to the necessary staff in accordance with billing compliance processes.
• Educates patients regarding protocol procedures and treatment regimen as needed and appropriate.
• Disseminates relevant study information to medical and nursing staff as it relates to patient care.
• Supports conduct of clinical trials, including travel to physician offices and all St. Luke’s campuses to explain studies/consent to patients and staff, obtain samples (urine, blood, etc.) as required by protocols, deliver drugs, review charts.
• Responsible for ordering and documentation of investigational and commercially available drugs supplied from the National Cancer Institute and other approved clinical trial sponsors as applicable.
• Professional conduct in the presence of subjects, research staff, sponsors, monitors, etc.
• Provide direction/training to other members of research staff as appropriate.
• Travel to required protocol meetings.
• For example, attendance at national cooperative group meetings or attendance at sponsor driven investigator meetings.
• Preparation and shipping of laboratory specimens to study (central) laboratories and maintenance of appropriate certifications related to this function (for example, IATA training).

PHYSICAL AND SENSORY REQUIREMENTS

• Requires sitting for up to seven hours per day, 4 hours at a time.
• Standing for up to 4 hours per day, 3 hours at time.
• Requires frequent fingering, handling and twisting and turning.
• Occasionally requires lifting, carrying and pushing and pulling objects weighing up to 20 pounds.
• Occasionally requires reaching above shoulder level.
• Must have the ability to hear as it relates to normal conversation, seeing as it relates to general vision.

EDUCATION

• Registered professional nurse required.

TRAINING AND EXPERIENCE

• Must have 2+ years direct oncology clinical trials experience.
• Clinical Research certification (e.g. SoCRA, ACRP, etc.) preferred.

St. Luke's University Health Network is an Equal Opportunity Employer.

Founded in 1872, St. Luke’s University Health Network (SLUHN) is a fully integrated, regional, non-profit network of more than 23,000 employees providing services at 16 campuses and 350+ outpatient sites. With annual net revenue in excess of $4 billion, the Network’s service area includes 11 counties in two states: Lehigh, Northampton, Berks, Bucks, Carbon, Montgomery, Monroe, Schuylkill and Luzerne counties in Pennsylvania and Warren and Hunterdon counties in New Jersey. St. Luke’s hospitals operate the largest network of trauma centers in Pennsylvania, with the Bethlehem Campus being home to St. Luke’s Children’s Hospital. SLUHN is the only Lehigh Valley-based health care system to earn Medicare’s five-star ratings (the highest) for quality, efficiency and patient satisfaction. It is both a Leapfrog Group and Healthgrades Top Hospital and a Newsweek World’s Best Hospital. The Network’s flagship University Hospital has earned the 100 Top Major Teaching Hospital designation from Premier 13 times total and eleven years in a row, including in 2023 when it was identified as THE #4 TEACHING HOSPITAL IN THE COUNTRY. In 2021, St. Luke’s was identified as one of the 15 Top Health Systems nationally. St. Luke’s is the ONLY health care institution in the Lehigh Valley to be named a Top Workplace regionally repeating the exclusive honor for the third year in a row. Also, for the third straight year, St. Luke’s has been a Top Workplaces in the Philadelphia Region by the Philadelphia Inquirer, ranking 9th in the large employer category for 2025 and the only health care system in PA to receive this award. In 2025, St. Luke’s was recognized as a national Top Workplaces by USA Today, three years in a row, including the 3rd best health care system in the nation in 2023 and 2024. Lastly, in 2025, St. Luke’s was named a Top Workplace in New Jersey for the third year in a row.