Oncology Regional Business Director - Great Lakes

Summit Therapeutics; Chicago (IL); On-site; USD 215,000 - 240,000; Full time

Job summary

Summit Therapeutics Inc. in Chicago, IL seeks an Oncology Regional Business Director to lead the launch and commercialization of ivonescimab within the Great Lakes region.

This leader will drive national sales strategies, recruit and coach a field sales team, and partner with Marketing and Medical Affairs to optimize execution. The role requires 10+ years in pharmaceutical/biotech sales, with 5+ years in oncology leadership, NSCLC experience preferred, and travel up to 75%.

Qualifications

• Strong coaching, leadership, and performance management skills.
• Excellent communication, presentation, and relationship-building skills.
• Experience analyzing sales data and translating insights into actionable business plans.
• Ability to travel up to 75%, including overnight travel, based on business needs.

Responsibilities

• Execute national sales strategies and business plans to achieve regional sales objectives and market share goals.
• Recruit, develop, coach, and retain a high-performing team of oncology account managers, fostering a culture of accountability, collaboration, and excellence.
• Lead regional launch readiness and execution, ensuring sales representatives are prepared to effectively promote ivonescimab and deliver a best-in-class customer experience.
• Monitor regional sales performance through KPIs, performance metrics, and business analytics; provide ongoing coaching and development to maximize team effectiveness.
• Develop strategic regional business plans and account strategies to optimize customer engagement and resource deployment.
• Partner closely with Marketing, Medical Affairs, Market Access, Commercial Operations, and other cross-functional teams to ensure aligned execution of commercial initiatives.
• Build and maintain strong relationships with key oncology customers, healthcare systems, and regional stakeholders.
• Gather and communicate customer insights, competitive intelligence, and market dynamics to inform commercial strategy and continuous improvement.
• Lead regional sales meetings, business reviews, and field coaching activities to reinforce strategic priorities and share best practices.
• Ensure all commercial activities are conducted in compliance with company policies, industry regulations, and applicable legal requirements.
• Manage regional travel, expenses, and resources responsibly.
• All other duties as assigned

Skills

Coaching

Leadership

Performance management

Communication

Presentation

Relationship-building

Education

Bachelor's degree in business, life sciences, or related field

Advanced degree preferred

Job description

Oncology Regional Business Director - Great Lakes

Chicago, IL

About Summit:

Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.

Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:

Non-small Cell Lung Cancer (NSCLC)

HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.

HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.

HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.

HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.

Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.

Overview of Role:

The Regional Business Director (RBD) will lead the successful launch and commercialization ofivonescimabwithinan assigned U.S. region. Reporting to theHead ofU.S. Sales, the RBDis responsible forexecuting national sales strategies, leading a high-performing team ofoncologyaccount managers,and driving regional performance to achieve commercialobjectives.

The RBD will recruit, develop, and coach a field sales team while fostering strong collaboration with Marketing, Market Access, Medical Affairs, and other cross-functional partners. This leader will serve as the voice of the field byprovidingcustomer insights, competitive intelligence, and market feedback tooptimizecommercial execution.

This role will reporttotheHead of US Sales.

Role and Responsibilities:

• Execute national sales strategies and business plans to achieve regionalsales objectivesand market share goals.
• Recruit, develop, coach, andretaina high-performing team ofoncologyaccountmanagers, fostering a culture of accountability, collaboration, and excellence.
• Lead regional launch readiness and execution, ensuring sales representatives are prepared to effectively promoteivonescimaband deliver a best-in-class customer experience.
• Monitor regional sales performance through KPIs, performance metrics, and business analytics; provide ongoing coaching and development to maximize team effectiveness.
• Develop strategic regional business plans and account strategies tooptimizecustomer engagement and resource deployment.
• Partner closely with Marketing, Medical Affairs, Market Access, Commercial Operations, and other cross-functional teams to ensure aligned execution of commercial initiatives.
• Build andmaintainstrong relationships with key oncology customers, healthcare systems, and regional stakeholders.
• Gather and communicate customer insights, competitive intelligence, and market dynamics to inform commercial strategy and continuous improvement.
• Lead regional sales meetings, business reviews, and field coaching activities to reinforce strategic priorities and share best practices.
• Ensure all commercial activities are conducted in compliance with company policies, industry regulations, and applicable legal requirements.
• Manage regional travel, expenses, and resources responsibly.
• All other duties as assigned

Experience, Education and Specialized Knowledge and Skills:

• Bachelor's degree in business,lifesciences, or a related field; advanced degree preferred.
• Minimumof10+ years of pharmaceutical or biotechnology sales experience, including 5+ years of oncology sales leadershipexperience
• Recent experience leading or supporting oncology product launches; NSCLC experience strongly preferred.
• Demonstrated success leading and developing high-performing oncology sales teams.
• Strong coaching, leadership, and performance management skills.
• Proven ability to analyze sales data and translate insights into actionable business plans.
• Excellent communication, presentation, and relationship-building skills.
• Experience collaborating effectively with cross-functional commercial and medical teams.
• Strong understanding of the oncology marketplace, customer landscape, and account-based selling.
• Ability to travel up to 75%, including overnight travel, based on business needs.

This is the pay for this position

Pay Transparency

$215,000 - $240,000 USD

Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at [e-mail] to obtain prior written authorization before referring any candidates to Summit.

Summit Therapeutics Inc.is an Equal Opportunity Employer and takes pride in creating and maintaining diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Summit Therapeutics’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.