Oncology Clinical Trials Manager — Radiopharma Ops

Alpha-9 Oncology; Boston (MA); On-site; USD 120,000 - 165,000; Full time

Benefits offered by this job

Salary and bonus

Equity

20 vacation days

5 sick days

Technology allowance

Commuter reimbursement

Retirement plan with employer matching

Extended health benefits

Paid holidays

Job summary

Alpha-9 Oncology seeks a highly motivated Clinical Operations Manager to support radiopharmaceutical trials with strong vendor management and hands-on execution. You will ensure activities align with protocols and regulatory requirements while partnering with the Clinical Operations Leader to drive trial delivery.

This role involves coordinating across teams, vendors, and sites, translating study strategy into actionable plans and delivering results in a fast-paced environment.

Qualifications

• 3–5 years of experience in clinical operations in pharma/biotech.
• Working knowledge of ICH/GCP regulations.
• Experience with early-stage oncology trials required; radiopharmaceutical experience preferred.
• Proven ability to identify and resolve issues and work independently.
• Excellent writing and communication skills are essential.

Responsibilities

• Track clinical trial timelines, budgets, metrics, and risks.
• Support CRO/vendor selection and site/country strategy.
• Develop site feasibility questionnaires and analyze results.
• Manage day-to-day vendor relationships including contracts and payments.
• Contribute to clinical documents: protocols, consent, manuals, reports, eCRF.
• Collaborate with Data Management, Clinical Sciences, and Development teams.
• Review site monitoring reports per the CRO oversight plan.
• Maintain TMF and review CRO TMF for completeness.
• Forecast clinical trial supplies to ensure site readiness.
• Assist Investigator and Study Coordinator meetings.
• Ensure adherence to regulatory requirements (ICH/FDA/EMA) and SOPs.
• Contribute to governance docs and work instructions.

Skills

Strong organization skills

Excellent writing & communication

Interpersonal skills

Problem solving

Independent work capability

Attention to detail

Cross-functional collaboration

Willingness to roll up sleeves

Education

Bachelor’s degree in Life Sciences

Advanced degree preferred

Job description

Alpha-9 Oncology seeks a highly motivated Clinical Operations Manager to support radiopharmaceutical trials with strong vendor management and hands-on execution. You will ensure activities align with protocols and regulatory requirements while partnering with the Clinical Operations Leader to drive trial delivery.

This role involves coordinating across teams, vendors, and sites, translating study strategy into actionable plans and delivering results in a fast-paced environment.