Oncology Clinical Program Lead — Early Development

Novartis Group Companies; Cambridge (MA); Hybrid; USD 249,000 - 462,000; Full time

Job summary

Novartis Group of Companies in Cambridge, MA is seeking a Senior CPL to lead strategic medical guidance for early oncology programs, from preclinical through Transition Decision Point. The role requires building clinical development plans and coordinating with global teams in Clinical Pharmacology, Biostatistics, and Regulatory Affairs.

The candidate will develop integrated development strategies, drive early clinical trials, ensure GCP compliance, and mentor junior CPLs while communicating

Qualifications

• At least 2 years of pharma/biotech oncology trials experience or equivalent academic translational oncology leadership.
• Experience in Radioligand Therapy (RLT) preferred.
• Recognized expert with external publications and international visibility.
• Strong interpretation of oncology preclinical data and PK/PD with biostatistics knowledge.
• Knowledge of GCP and worldwide regulatory requirements for clinical trials.
• Excellent medical/scientific writing and strategic thinking.
• Ability to lead and inspire global, multidisciplinary teams.
• Commitment to ethical patient outcomes and strong English communication.

Responsibilities

• Provides strategic medical leadership for oncology programs from preclinical through TDP.
• Develops clinical development strategies integrating cross-functional expertise to optimize programs.
• Aligns with DALs, DEV, S&G, and Commercial teams on IDPA and development plans.
• Leads cross-functional project teams and mentors CPLs in a global setting.
• Interprets preclinical data and guides regulatory strategy and study design.
• Ensures GCP compliance and robust medical/scientific reporting.

Skills

Medical writing

Clinical development leadership

Oncology clinical trials

GCP knowledge

Strategic thinking

Team leadership

PK/PD knowledge

Biostatistics knowledge

English communication

Education

MD or DO degree

Board-certification in oncology

PhD-level science

Job description

Novartis Group of Companies in Cambridge, MA is seeking a Senior CPL to lead strategic medical guidance for early oncology programs, from preclinical through Transition Decision Point. The role requires building clinical development plans and coordinating with global teams in Clinical Pharmacology, Biostatistics, and Regulatory Affairs.

The candidate will develop integrated development strategies, drive early clinical trials, ensure GCP compliance, and mentor junior CPLs while communicating