On-Site Process Development Engineer: Purification

Regeneron Pharmaceuticals, Inc (USA); Village of Tarrytown (NY); On-site; USD 80,000 - 131,000; Full time

Job summary

Regeneron Pharmaceuticals, Inc (USA) in Tarrytown, NY is seeking a Process Development Engineer I to join the Late-Stage Purification Development team (PMPD) on-site. You will design and execute bench- and pilot-scale experiments for harvest, affinity chromatography, and viral inactivation of recombinant proteins using QbD principles.

You will collaborate across PD and manufacturing, drive data-driven decisions, and contribute to process automation, lab safety, and training of students and peers.

Qualifications

• Bachelor's or Master's degree in Chemical Engineering, Biochemical Engineering, Biochemistry, or a related field.
• 0-2 years of recombinant protein purification experience.
• Hands-on experience with depth filtration, disc stack centrifugation, column chromatography, virus retentive filtration, ultrafiltration/diafiltration, and buffer preparation.
• Solid understanding of purifying monoclonal antibodies or other biopharmaceuticals.
• Experience with process automation, hardware, control logic, and/or HMI development.

Responsibilities

• Design and execute experiments at bench and pilot scale.
• Analyze data, draw conclusions, and propose next steps.
• Document results in lab notebooks and reports.
• Serve as purification development SME during manufacturing process transfer.
• Collaborate cross-functionally to enable a robust manufacturing process.
• Support technology development, such as automating pilot-scale unit operations and building data workflows.
• Train and mentor peers, co-ops, and interns in experiments and data analysis.

Skills

Protein purification

Depth filtration

Disc stack centrifugation

Column chromatography

Virus retentive filtration

Ultrafiltration

Process automation

HMI development

Akta chromatography systems

Python

Empower

Unicorn

JMP

LIMS

PI Historian

Ignition

Education

Bachelor's or Master's degree in Chemical Engineering, Biochemical Engineering, Biochemistry, or related field

Tools

Akta chromatography systems

HPLC

UPLC

Empower

Unicorn

JMP

LIMS

Python

Ignition

PI Historian

Job description

Regeneron Pharmaceuticals, Inc (USA) in Tarrytown, NY is seeking a Process Development Engineer I to join the Late-Stage Purification Development team (PMPD) on-site. You will design and execute bench- and pilot-scale experiments for harvest, affinity chromatography, and viral inactivation of recombinant proteins using QbD principles.

You will collaborate across PD and manufacturing, drive data-driven decisions, and contribute to process automation, lab safety, and training of students and peers.