Oligonucleotide Process Research Associate I/II

Ionis-Pharmaceuticals; Carlsbad (CA); On-site; USD 69,000 - 110,000; Full time

Benefits offered by this job

Excellent benefits package

Job summary

Ionis Pharmaceuticals in Carlsbad, CA, is seeking a Research Associate I / II, Manufacturing Process Research to support development and execution of oligonucleotide manufacturing processes. This entry-level scientist will work under experienced scientists and contribute to experiments and data documentation.

The role offers exposure to solid-phase synthesis, purification, and analytical data review, with growth opportunities within a team focused on RNA-targeted medicines.

Qualifications

• Bachelor’s degree in chemistry, chemical engineering, biochemistry, biology, pharmaceutical sciences, or related field.
• For Research Associate II, at least 2 years of relevant experience.

Responsibilities

• Execute defined laboratory experiments supporting oligonucleotide process development and manufacturing research.
• Perform laboratory-scale solid-phase synthesis and related operations.
• Prepare, process, and purify oligonucleotide materials using chromatography and filtration.
• Support process-development programs across antisense, siRNA, and conjugated modalities.
• Record procedures, observations, results, and conclusions accurately in ELN.

Skills

Laboratory techniques

Data analysis

Documentation

Collaborative work

Education

Bachelor’s degree in chemistry or related field

Tools

HPLC

LC-MS

Electronic lab notebook (ELN)

Job description

Ionis Pharmaceuticals in Carlsbad, CA, is seeking a Research Associate I / II, Manufacturing Process Research to support development and execution of oligonucleotide manufacturing processes. This entry-level scientist will work under experienced scientists and contribute to experiments and data documentation.

The role offers exposure to solid-phase synthesis, purification, and analytical data review, with growth opportunities within a team focused on RNA-targeted medicines.