Ocular Research Scientist, Retina & RNA Therapeutics

Automatic Data Processing, Inc.; San Diego (CA); On-site; USD 110,000 - 130,000; Full time

Job summary

ADARx Pharmaceuticals, Inc. in San Diego seeks a Senior Scientist I in Ocular Research to advance preclinical programs addressing AMD and retinal diseases. You will lead efforts in ocular biology, in vivo and in vitro models, and translational assessments of oligonucleotide therapies.

The role requires hands-on experience with ERG, OCT, RNAscope, and single-cell RNA sequencing, plus strong collaboration with discovery biology and non-clinical safety teams. A Ph.D.

Qualifications

• Ph.D. in Neuroscience, Ophthalmology/Vision Science, or Molecular Biology.
• 3-4 years biotechs/pharma experience in retinal or ocular drug discovery.
• Strong knowledge of retinal anatomy, physiology, and ocular pharmacology.
• Experience with in vivo ocular rodent models and tissue microdissection.
• Hands-on expertise with ocular functional/structural assessments (ERG, OCT).
• Experience with RNAscope and single-cell RNA sequencing analyses.

Responsibilities

• Lead and participate in discovery projects for ocular siRNA and RNA editing therapies.
• Develop and characterize ocular mouse models relevant to AMD and other retinal diseases.
• Establish ocular in vivo systems to screen siRNAs in rodents.
• Perform animal monitoring, tissue collection, and sample processing per protocols.
• Conduct microdissection of ocular tissues (retina, RPE/choroid).
• Perform ERG, OCT, fundus imaging, and other ocular imaging/functional assessments.
• Design/perform RNAscope to study distribution and expression in ocular tissues.
• Plan/execute single-cell RNA sequencing studies and integrate with other data.
• Collaborate with multidisciplinary teams across discovery biology and safety.
• Maintain records and present findings to teams.

Skills

Ocular biology

In vivo rodent models

ERG/OCT imaging

RNA sequencing

RNAscope

Cell culture

Data analysis

Education

Ph.D. in Neuroscience, Ophthalmology/Vision Science, Molecular Biology

Job description

ADARx Pharmaceuticals, Inc. in San Diego seeks a Senior Scientist I in Ocular Research to advance preclinical programs addressing AMD and retinal diseases. You will lead efforts in ocular biology, in vivo and in vitro models, and translational assessments of oligonucleotide therapies.

The role requires hands-on experience with ERG, OCT, RNAscope, and single-cell RNA sequencing, plus strong collaboration with discovery biology and non-clinical safety teams. A Ph.D.