NortheasternU_Marine_Science_Center_MA_US_Bioinformatician

EvolDir; Massachusetts; Vor Ort; USD 90.000 - 130.000; Vollzeit

Zusammenfassung

EvolDir, based in Nahant, MA, seeks a Bioinformatician to join the Marine Macrogenomics consortium. You will develop and maintain scalable pipelines for large-scale genomic data, focusing on short-read alignment and population-level inference, collaborating with wet-lab and computational teams.

The role requires a Master’s in a related field and 2–5 years of hands-on bioinformatics experience, with proficiency in BWA/STAR, SAMtools/GATK, Snakemake or Nextflow, and scripting in Python/R.

Qualifikationen

• Master’s degree in biology, ecology and evolution, bioinformatics, computational biology, genetics, or related field.
• 2–5 years of hands-on bioinformatics experience with genomics.
• Proficiency with short-read aligners (BWA, Bowtie2, STAR).
• Experience with SAMtools, GATK, Picard.
• Experience with pipeline tools (Snakemake/Nextflow).
• Strong scripting in Python, R, Bash; Unix/Linux comfort.
• Experience with HPC/HTC environments and schedulers (SLURM/HTCondor).
• Experience using APIs for data transfer or large data movement.
• Familiarity with version control and containerization (Git, Docker/Singularity).
• Track record of contributing to published research.

Aufgaben

• Design, build, and maintain scalable bioinformatics pipelines across population genomic datasets.
• Align short-read data to reference genomes and assess mapping quality.
• Perform variant calling, filtering, and QC in population genomics.
• Document workflows for reproducibility and publication.
• Develop tutorials and assist with website projects; collate public data with metadata.
• Collaborate with wet-lab and computational team members to meet data standards.

Kenntnisse

Bioinformatics

Short-read alignment

Python

R

Bash

Unix/Linux

HPC/HTC

Snakemake

Nextflow

SLURM/HTCondor

APIs/data transfer

Ausbildung

Master's degree in Biology or related field

PhD or 3+ years post-master's preferred

Tools

BWA

Bowtie2

STAR

SAMtools

GATK

Picard

Snakemake

Nextflow

Git

Docker/Singularity

Jobbeschreibung

Job SummaryWe are seeking a skilled Bioinformatician to join our consortium in Marine Macrogenomics, which seeks to create a database of interoperable population genomic data for 5,000 genomes from 100 species. The successful candidate will play a central role in developing and maintaining scalable computational pipelines for the analysis of large-scale genomic datasets, with a focus on short-read alignment and population-level inference. This is an exciting opportunity to contribute to cutting-edge research in ecological and conservation genomics.Minimum QualificationsRequired- Master's degree in Biology, Ecology and Evolution, Bioinformatics, Computational Biology, Genetics, or a related field- 2-5 years of hands-on experience in bioinformatics, with demonstrated work in genomics- Proficiency in short-read alignment tools such as BWA, Bowtie2, and STAR- Familiarity with downstream processing tools such as SAMtools, Genome Analysis Toolkit (GATK), and Picard- Experience writing pipelines using workflow management systems such as Snakemake or Nextflow- Solid scripting skills in Python, R, and Bash- Comfort working on the command line, including in a Unix/Linux environment- Familiarity with high-performance computing (HPC) and high-throughput computing (HTC) environments and job schedulers such as SLURM and HTCondor- Experience using application programming interfaces (APIs) to send and receive data and/or experience using tools to transfer large amounts of data between remote serversPreferred- PhD or 3 years of post-Master's experience preferred- Experience with population genomic analyses and tools such as ANGSD, PLINK, ADMIXTURE, TreeMix, or similar platforms- Familiarity with handling non-model organism genomes or low-coverage sequencing data- Experience with version control systems such as Git and containerization technologies including Docker and Singularity/Apptainer- Track record of contributing to published researchKey Responsibilities & Accountabilities- Collaborate and coordinate with members of the network, including wet lab and computational team members, to define data standards, ensure analytical reproducibility, and assist with project goals- Design, build, and maintain reproducible bioinformatics pipelines capable of scaling across many population genomic datasets- Align short-read sequencing data, including whole-genome and Restriction Site Associated DNA Sequencing (RADseq) datasets, to reference genomes using standard and emerging tools, and evaluate mapping quality across diverse datasets- Perform downstream population genomic analyses, including variant calling, filtering, and quality control- Document pipelines and analyses clearly for internal use and publication- Develop educational tutorials and assist with website development- Collate publicly available data and metadata, corresponding with authors as necessary to ensure data standardsApply here: https://northeastern.wd1.myworkdayjobs.com/careers/job/Nahant-MA/Bioinformatician---Lotterhos-Lab_R142449Review of applications starts on October 1, with a start date as soon as possible.