NGS Scientist

JobDiva, Inc.; Boston (MA); On-site; USD 65,000 - 79,000; Full time

Benefits offered by this job

ACA-compliant supplemental package

Job summary

Primary Talent Partners is seeking an NGS Scientist to join our pharmaceutical client in Boston, MA on a 6-month contract with potential extensions. The role focuses on next-generation sequencing library preparation, RNA-seq, scRNA-seq, and snRNA-seq across therapeutic areas within the Cardiometabolic Research team.

You will conduct experiments to identify and validate drug targets, support assay design and data analyses, and present results in oral and written form.

Qualifications

• B.S. and/or M.S. with 3-5 years of laboratory research experience.
• Molecular biology mastery of nucleic acid extraction and purification, QC and qPCR.
• Strong background in NGS technologies including RNA-seq (bulk) and amplicon-seq.
• Experience with single-cell and single-nucleus RNA-seq library preparation; familiarity with multiple platforms like 10X Genomics Chromium, Illumina PIP-seq, ScaleBio, Parse Biosciences.

Responsibilities

• Perform RNA-seq, scRNA-seq, snRNA-seq library preps for all CMR groups.
• Design and execute molecular and cell biology experiments.
• Support assay design, optimization, validation and data analyses.
• Troubleshoot and analyze complex data for drug discovery projects.
• Present results and conclusions both orally and in writing.

Skills

RNA-seq

scRNA-seq

snRNA-seq

NGS library prep

qPCR

Education

B.S./M.S. in biological or biochemical sciences

Tools

10X Genomics Chromium

Illumina PIP-seq

ScaleBio

Parse Biosciences

Mantis

Integra systems

Liquid Handlers

SPTLabtech Firefly

Tecan

Job description

Primary Talent Partners has a new contract opening for a NGS Scientist to join our pharmaceutical client in Boston, MA. This is a 6-month contract to start with the potential for extensions.

Pay

$47.00 - $57.00/hr; W2 contract, no PTO, no Benefits. ACA-compliant supplemental package available for enrollment. Candidates must be legally authorized to work in the United States and must be able to sit on Primary Talent Partners W2 without sponsorship.

Description

Come join the Cardiometabolic Research (CMR) team. We are focused on the discovery and early phase clinical development of biologic, small molecule, oligonucleotide, and cell therapies for treatment of diabetes, obesity, cardiovascular disease, and associated metabolic disorders.

• The Data Science team within CMR is seeking someone with wide-ranging experience in next-generation sequencing library preparation to help achieve our research goals.
• The successful candidate will be responsible for RNA-seq, scRNA-seq, snRNA-seq, and other types of -seq library preparations for all CMR groups.
• This will be a cross-therapeutic area role encompassing opportunities to impact science in the Boston team.
• Conduct experiments to identify and validate drug targets.
• Support assay design, optimization, validation, and data analyses.
• Design and execute molecular and cell biology experiments.
• Troubleshoot and analyze complex data in support of drug discovery projects.
• Presentation of results and conclusions both orally and written.

Job Requirements

• B.S. and/or M.S. in biological or biochemical sciences (or a related field) with 3-5 years of laboratory research experience.
• Molecular biology mastery of nucleic acid extraction and purification, quantification, NGS library preparation/QC, and qPCR.
• Strong background in NGS technologies and their applications, including quantification, sequencing, and data QC (preferably Illumina). Direct experience with RNA-seq (bulk) and amplicon-seq.
• Direct experience with single-cell and single-nucleus RNA-seq library preparation is required. Candidates must be familiar with multiple scRNA-seq/snRNA-seq platforms (e.g., 10X Genomics Chromium, Illumina PIP-seq, ScaleBio, or Parse Biosciences).

Additional Skills/Preferences

• Familiarity with CRISPR-based gene editing and high-throughput screening is a plus.
• Experience with automation is a plus (Mantis, Integra systems, Liquid Handlers, SPTLabtech Firefly, Tecan, etc).
• Strong organizational, time management, and communication skills.
• Experience with documentation in electronic notebook software.

Primary Talent Partners is an Equal Opportunity / Aff... All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, age, national origin, disability, protected veteran status, gender identity, or any other factor protected by applicable federal, state, or local laws.

If you are a person with a disability needing assistance with the application or at any point in the hiring process, please contact us at [e-mail]

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