NGS Lab Operations Leader - Cancer Diagnostics

Predicine; Hayward, Northern (CA, KY); Hybrid; USD 170,000 - 230,000; Full time

Job summary

Predicine seeks an experienced Manager/Senior Manager, NGS Lab to lead day-to-day wet-lab operations, staff development, and cross-functional collaboration. You will oversee sample prep, sequencing, QC, and overall lab performance across multiple NGS assays, ensuring timely, compliant execution.

The role requires strong NGS technical expertise, people leadership, and operational management to scale laboratory operations and maintain audit readiness onsite in Hayward, CA.

Qualifications

• Minimum 5+ years of relevant molecular biology/NGS laboratory experience with leadership.
• Experience in CLIA/CAP-regulated molecular diagnostics or NGS labs is preferred.
• Strong knowledge of NGS workflows and QC processes.

Responsibilities

• Lead daily wet-lab operations, including sample accessioning, nucleic acid extraction, library prep, sequencing and QC.
• Manage scheduling, staffing, batching, equipment, and priorities to meet timelines and throughput targets.
• Coach, train, and develop staff; ensure proper staffing, competency, and workload distribution.
• Monitor performance metrics, investigate deviations, support CAPA and reprocessing decisions.
• Ensure SOPs, quality requirements, GLP and regulatory readiness; support audits and inspections.
• Provide technical leadership and troubleshoot NGS workflows, reagents, and processes.
• Drive continuous improvement and transfer new assays from R&D to operations.

Skills

NGS workflows

Laboratory management

Troubleshooting

Multitasking in fast-paced environment

Education

Bachelor's degree

Master's degree or PhD

Tools

Illumina NovaSeq

LIMS/BioLIMS

Laboratory automation

CAPA

Job description

Predicine seeks an experienced Manager/Senior Manager, NGS Lab to lead day-to-day wet-lab operations, staff development, and cross-functional collaboration. You will oversee sample prep, sequencing, QC, and overall lab performance across multiple NGS assays, ensuring timely, compliant execution.

The role requires strong NGS technical expertise, people leadership, and operational management to scale laboratory operations and maintain audit readiness onsite in Hayward, CA.